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Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival.
TLDR
It is suggested that lung transplantation should be considered in a subset of patients who remain in NYHA functional class III or IV or in those who cannot achieve a significant hemodynamic improvement after three months of epoprostenol therapy, or both. Expand
Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity
TLDR
The authors individualise the computer tomography-defined syndrome of combined pulmonary fibrosis and emphysema characterised by subnormal spirometry, severe impairment of gas exchange, high prevalence of pulmonary hypertension, and poor survival. Expand
Prognostic factors for survival in human immunodeficiency virus-associated pulmonary arterial hypertension.
TLDR
Patients with severe human immunodeficiency virus-associated PAH should be considered for long-term epoprostenol infusion in association with CART, according to multivariate analysis and prognostic factors. Expand
Pulmonary hypertension associated with sarcoidosis: mechanisms, haemodynamics and prognosis
TLDR
Two very different phenotypes of sarcoidosis combined with PH are observed depending on the presence or absence of pulmonary fibrosis. Expand
Combined pulmonary fibrosis and emphysema syndrome in connective tissue disease.
TLDR
CPFE warrants inclusion as a novel, distinct pulmonary manifestation within the spectrum of CTD-associated lung diseases in smokers or former smokers, especially in patients with RA or SSc. Expand
Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity.
TLDR
In patients with antisynthetase syndrome, the phenotype and the survival were correlated with the anti-ARS specificity, and patient survival was significantly lower in patients with anti-PL7/12 rather than anti-Jo1. Expand
Sarcoidosis
TLDR
Several new insights have been made, particularly with regards to the diagnosis and care of some important manifestations of sarcoidosis, and the elucidation of relevant biomarkers, reliable endpoints, and new efficient treatments are predicted. Expand
Clinical characteristics and prognostic factors of pulmonary MALT lymphoma
TLDR
The survival data confirm the indolent nature of pulmonary MALT lymphoma and suggest treatment with cyclophosphamide or anthracyclin was associated with shorter progression-free survival, when compared with chlorambucil. Expand
Role of nitric oxide in hepatopulmonary syndrome in cirrhotic rats.
TLDR
Findings suggest that HPS and the associated reduced response to pulmonary vasoconstrictors seen in untreated cirrhotic rats are related to increased pulmonary NO production dependent primarily on increases in the expression and activities of inducible NOS within pulmonary intravascular macrophages. Expand
Imaging in sarcoidosis.
TLDR
Thin-section high-resolution computed tomographic scans more clearly elucidate the intrathoracic lesions observed in sarcoidosis and may discriminate active inflammation from end-stage fibrosis and discriminate alveolitis from fibrosis. Expand
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