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Small-molecule agonists and antagonists of F-box protein–substrate interactions in auxin perception and signaling
The regulation of gene expression by the hormone auxin is a crucial mechanism in plant development. We have shown that the Arabidopsis F-box protein TIR1 is a receptor for auxin, and our recentExpand
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Identification and functional analysis of bifunctional ent‐kaurene synthase from the moss Physcomitrella patens
ent‐Kaurene is the key intermediate in biosynthesis of gibberellins (GAs), plant hormones. In higher plants, ent‐kaurene is synthesized successively by copalyl diphosphate synthase (CPS) andExpand
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Rational design of an auxin antagonist of the SCF(TIR1) auxin receptor complex.
The plant hormone auxin is a master regulator of plant growth and development. By regulating rates of cell division and elongation and triggering specific patterning events, indole 3-acetic acidExpand
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Yokonolide B, a Novel Inhibitor of Auxin Action, Blocks Degradation of AUX/IAA Factors*
Yokonolide B (YkB; also known as A82548A), a spiroketal-macrolide, was isolated from Streptomyces diastatochromogenes B59 in a screen for inhibitors of β-glucoronidase expression under the control ofExpand
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Characterization of Terfestatin A, a New Specific Inhibitor for Auxin Signaling1[w]
Terfestatin A (TrfA), terphenyl-β-glucoside, was isolated from Streptomyces sp. F40 in a forward screen for compounds that inhibit the expression of auxin-inducible genes in Arabidopsis (ArabidopsisExpand
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Arabidopsis Aux/IAA genes are involved in brassinosteroid-mediated growth responses in a manner dependent on organ type.
We examined whether auxin/indole-3-acetic acid (Aux/IAA) proteins, which are key players in auxin-signal transduction, are involved in brassinosteroid (BR) responses. iaa7/axr2-1 and iaa17/axr3-3Expand
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Using the pER8:GUS reporter system to screen for phytoestrogens from Caesalpinia sappan.
Arabidopsis thaliana pER8:GUS, a low-cost, highly efficient, and convenient transgenic plant system, was used to assay the estrogen-like activity of 30 traditional Chinese medicines. The MeOH extractExpand
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Endogenous Diterpenes Derived from ent-Kaurene, a Common Gibberellin Precursor, Regulate Protonema Differentiation of the Moss Physcomitrella patens1[W][OA]
Gibberellins (GAs) are a group of diterpene-type plant hormones biosynthesized from ent-kaurene via ent-kaurenoic acid. GAs are ubiquitously present in seed plants. The GA signal is perceived andExpand
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Pheophytin a, a low molecular weight compound found in the marine brown alga Sargassum fulvellum, promotes the differentiation of PC12 cells
We identified and characterized a neurodifferentiation compound from the marine brown alga Sargassum fulvellum collected from the Japanese coastline. Several instrumental analyses revealed theExpand
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