A diagnosis of malignant struma ovarii should be reserved for lesions that exhibit the full range of changes seen in thyroid carcinoma arising in the cervical thyroid, and will probably become less frequent as the more commonly encountered proliferative struma Ovarii are recognized.Expand
The clinical and pathologic findings of 16 examples of a distinctive stromal tumor of the breast designated as“myofibroblastoma” are reported, and the clinical significance lies primarily in its recognition as a distinctive benign neoplasm.Expand
The findings in this study provide a rationale for classifying noninvasive endometrial proliferations primarily on the basis of cytologic atypia since this is the most useful criterion in predicting the likelihood of progression to carcinoma.Expand
Purely mesenchymal tumors, such as those derived from smooth muscle and endometrial stroma, are considered, as are benign and malignant neoplasms in which there are mixtures of epithelium and connective tissue.Expand
The size of the primary tumor and presence of vein invasion showed a slight correlation with the patient's prognosis but no correlation was found with increasing degrees of cellular atypism and x‐ray irradiation appeared to be of benefit.Expand
The most useful criterion for distinguishing adenofibroma from adenosarcoma was the frequency of mitotic figures found in the stroma, and the only morphologic feature that correlated with aggressive behavior of adenosarena was deep myometrial invasion.Expand
The presence of atypia in epithelial hyperplasia is a significant factor in increasing the likelihood of the development of subsequent invasive carcinoma, particularly in patients with AIDH.Expand
This distinctive form of metaplastic carcinoma with direct transition to a cartilaginous and/or osseous stromal matrix without an intervening spindle cell zone or osteoclastic giant cells is designated as "matrix-producing carcinoma" (MPC).Expand
The findings in this study provide a rationale for classifying noninvasive endometrial proliferations primarily on the basis of cytologic atypia since this is the most useful criterion in predicting the likelihood of progression to carcinoma.Expand
Findings, in conjunction with histopathologic features, and ultrastructural observations from three cases, support myoepithelium as an integral component of SpCC.Expand