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Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations.
Previously, we examined the relationship between protamine gene variations and human male infertility. In this study, we show specific variability in the transition nuclear protein genes (TNPs) ofExpand
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A community cluster of influenza A(H1N1)pdm09 virus exhibiting cross-resistance to oseltamivir and peramivir in Japan, November to December 2013.
Six influenza A(H1N1)pdm09 viruses were detected in Sapporo, Japan, between November and December 2013. All six viruses possessed an H275Y substitution in the neuraminidase protein, which confersExpand
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Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein.
Recently we cloned the Hanp1 cDNA that encodes a histone H1-like haploid germ cell-specific nuclear protein in the mouse. Homozygous Hanp1 mutant male mice were infertile, while females were fertile.Expand
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Control of Mouse hils1 Gene Expression During Spermatogenesis: Identification of Regulatory Element by Transgenic Mouse
Abstract Histone H1-like protein in spermatids 1 (Hils1) is a testis- specific histone H1-like protein exclusively expressed in haploid spermatids and should be involved in chromatin remodelingExpand
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Identification of human HAPRIN potentially involved in the acrosome reaction.
The acrosome reaction in sperm is an exocytotic event required for fertilization. Previously, we isolated a novel haploid-germ-cell-specific gene in the mouse; this gene, named haprin, encodes theExpand
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Cloning and characterization of a mouse spergen-1 localized in sperm mitochondria.
Development of spermatozoa is a complex process involving specific morphological formation of flagella, nucleus and mitochondria. Although detailed morphological observations of these events areExpand
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Rosbin: A Novel Homeobox-Like Protein Gene Expressed Exclusively in Round Spermatids
Abstract Mammalian spermiogenesis is a complex process occurring in a highly coordinated fashion within the seminiferous tubules. To elucidate the molecular mechanisms controlling haploid germ cellExpand
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Nodal paralogues underlie distinct mechanisms for visceral left–right asymmetry in reptiles and mammals
Unidirectional fluid flow generated by motile cilia at the left–right organizer (LRO) breaks left–right (L–R) symmetry during early embryogenesis in mouse, frog and zebrafish. The chick embryo,Expand
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Molecular cloning and characterization of the human orthologue of the oppo 1 gene encoding a sperm tail protein.
We report here the molecular cloning and characterization of a human orthologue of oppo 1, a mouse gene encoding a male germ-cell-specific sperm tail protein, and the organization of its genomicExpand
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Sperm flagella protein components: Human meichroacidin constructed by the membrane occupation and recognition nexus motif
Background and AimsIn a previous study, the authors of the present study cloned mouse meichroacidin (MCA), which is expressed in stages of spermatogenesis from pachytene spermatocytes through roundExpand
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