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Five-year efficacy and safety of photodynamic therapy with Photofrin in Barrett's high-grade dysplasia.
BACKGROUND Barrett's esophagus (BE) with high-grade dysplasia (HGD) is a risk factor for development of esophageal carcinoma. Photodynamic therapy (PDT) with Photofrin (PHO) has been used toExpand
Neutropenic enterocolitis. Clinical diagnosis and treatment
Review of the consultation records of the Gastrointestinal Surgical Oncology service at Roswell Park Memorial Institute from 1982 to 1987 revealed 22 patients with a finical diagnosis of neutropenicExpand
Predictive factors associated with long-term survival in patients with neuroendocrine tumors of the pancreas
BackgroundNeuroendocrine tumors of the pancreas are rare tumors. We identified predictive factors that are associated with long-term survival (≥5 years).MethodsFifty patients with a diagnosis ofExpand
Surgical Management and Outcome in Primary Adenocarcinoma of the Small Bowel
BackgroundPrimary adenocarcinoma of the small bowel is a rare malignancy and is associated with poor survival outcome. Patient, tumor and treatment-related factors were analyzed for their associationExpand
Photodynamic therapy (PDT) using HPPH for the treatment of precancerous lesions associated with barrett's esophagus
Photodynamic therapy (PDT) with porfimer sodium, FDA approved to treat premalignant lesions in Barrett's esophagus, causes photosensitivity for 6–8 weeks. HPPH (2‐[1‐hexyloxyethyl]‐2‐devinylExpand
Photodynamic therapy with porfimer sodium versus thermal ablation therapy with Nd:YAG laser for palliation of esophageal cancer: a multicenter randomized trial.
BACKGROUND Photodynamic therapy (PDT) is a different type of laser treatment from Nd:YAG thermal ablation for palliation of dysphagia from esophageal cancer. METHODS In this prospective,Expand
Population pharmacokinetics of the photodynamic therapy agent 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a in cancer patients.
Photodynamic therapy is an effective and often curative treatment for certain solid tumors. The porphyrin-based photosensitizer Photofrin, the only Food and Drug Administration-approved drug for thisExpand
Laser palliation for colorectal carcinoma.
A review was conducted of 27 patients with colorectal carcinoma treated palliatively with endoscopic neodymium:yttrium-aluminium-garnet (Nd:YAG) laser. There were 25 rectal carcinomas and 2 primaryExpand
Oxaliplatin in combination with protracted-infusion fluorouracil and radiation: report of a clinical trial for patients with esophageal cancer.
PURPOSE To identify a dose and schedule of oxaliplatin (OXP) to be safely administered in combination with protracted-infusion (PI) fluorouracil (5-FU) and external-beam radiation therapy (XRT) forExpand
Esophageal resection for carcinoma in patients older than 70 years
BackgroundA larger number of older patients are presenting as candidates for esophageal resection. An aggressive surgical approach in this population is controversial.MethodsFour hundred thirteenExpand