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Human mitochondrial DNA is packaged with TFAM.
Mitochondrial transcription factor A (TFAM), a member of the high mobility group proteins, is essential for maintenance of mitochondrial DNA (mtDNA). Most TFAM and mtDNA (both of which are normallyExpand
Human Leukocyte-derived Arginine Aminopeptidase
In this study we report the cloning and characterization of a novel human aminopeptidase, which we designate leukocyte-derived arginine aminopeptidase (L-RAP). The sequence encodes a 960-amino acidExpand
Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells.
A suppressor tRNA(Tyr) and mutant tyrosyl-tRNA synthetase (TyrRS) pair was developed to incorporate 3-iodo-L-tyrosine into proteins in mammalian cells. First, the Escherichia coli suppressorExpand
Phosphorylation of alphaB-crystallin in response to various types of stress.
Phosphorylation of alphaB-crystallin, a member of the hsp27 family, in human glioma (U373 MG) cells was stimulated by exposure of the cells to various stimuli, which included heat, arsenite, phorbolExpand
Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells
Phagocytic removal of cells undergoing apoptosis is necessary for animal development and tissue homeostasis. Draper, a homologue of the Caenorhabditis elegans phagocytosis receptor CED‐1, isExpand
Diversity of Innate Immune Recognition Mechanism for Bacterial Polymeric meso-Diaminopimelic Acid-type Peptidoglycan in Insects
In Drosophila, the synthesis of antimicrobial peptides in response to microbial infections is under the control of the Toll and immune deficiency (Imd) signaling pathway. The Toll signaling pathwayExpand
Purification of Polyglutamine Aggregates and Identification of Elongation Factor-1α and Heat Shock Protein 84 as Aggregate-Interacting Proteins
Aggregates of green fluorescent protein (GFP)-fused truncated N-terminal huntingtin containing abnormally long polyglutamine tracts (150 repeats of glutamine residue) were purified from anExpand
PRMT1 is required for RAP55 to localize to processing bodies
In eukaryotic cells, components of messenger ribonucleoproteins (mRNPs) are often detected in cytoplasmic granules, such as processing bodies (P-bodies) and stress granules (SGs) whereExpand
Phosphorylation of αB-Crystallin in Response to Various Types of Stress*
Phosphorylation of αB-crystallin, a member of the hsp27 family, in human glioma (U373 MG) cells was stimulated by exposure of the cells to various stimuli, which included heat, arsenite, phorbolExpand
Landscape of the complete RNA chemical modifications in the human 80S ribosome
Abstract During ribosome biogenesis, ribosomal RNAs acquire various chemical modifications that ensure the fidelity of translation, and dysregulation of the modification processes can cause proteomeExpand
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