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2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up,…
- H. Calkins, K. Kuck, +43 authors D. Wilber
- Europace : European pacing, arrhythmias, and…
- 1 April 2012
During the past decade, catheter ablation of atrial fibrillation (AF) has evolved rapidly from an investigational procedure to its current status as a commonly performed ablation procedure in many… Expand
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Recent studies have indicated the existence of tumorigenesis barriers that slow or inhibit the progression of preneoplastic lesions to neoplasia. One such barrier involves DNA replication stress,… Expand
CSK: a protein-tyrosine kinase involved in regulation of src family kinases.
- M. Okada, S. Nada, Y. Yamanashi, T. Yamamoto, H. Nakagawa
- Chemistry, Medicine
- The Journal of biological chemistry
- 25 December 1991
The functions of src family protein-tyrosine kinases are thought to be regulated negatively by the phosphorylation of highly conserved tyrosine residues close to their carboxyl termini. Recently we… Expand
Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate.
Although (-)-epigallocatechin gallate (EGCG) has been reported to induce apoptosis in a variety of tumor cells, detailed mechanisms remain to be explored. In the present study, we investigated the… Expand
A novel radiofrequency ablation catheter using contact force sensing: Toccata study.
OBJECTIVES The aim of this multicenter study was to evaluate the device- and procedure-related safety of a novel force-sensing radiofrequency (RF) ablation catheter capable of measuring the real-time… Expand
Pathophysiologic basis of autonomic ganglionated plexus ablation in patients with atrial fibrillation.
- H. Nakagawa, B. Scherlag, E. Patterson, A. Ikeda, D. Lockwood, W. Jackman
- Heart rhythm
- 1 December 2009
The intrinsic cardiac autonomic nervous system (ganglionated plexuses [GP]) plays a significant role in the initiation and maintenance of atrial fibrillation (AF) in both experimental models and AF… Expand
Irrigated Radiofrequency Catheter Ablation Guided by Electroanatomic Mapping for Recurrent Ventricular Tachycardia After Myocardial Infarction: The Multicenter Thermocool Ventricular Tachycardia…
Background— Recurrent ventricular tachycardia (VT) is an important cause of mortality and morbidity late after myocardial infarction. With frequent use of implantable cardioverter-defibrillators,… Expand
Novel Contact Force Sensor Incorporated in Irrigated Radiofrequency Ablation Catheter Predicts Lesion Size and Incidence of Steam Pop and Thrombus
- K. Yokoyama, H. Nakagawa, +8 authors W. Jackman
- Circulation. Arrhythmia and electrophysiology
- 1 December 2008
Background—An open-irrigated radiofrequency (RF) ablation catheter was developed to measure contact force (CF). Three optical fibers measure microdeformation of the catheter tip. The purpose of this… Expand
A New Strategy of High-Speed Screening and Quantitative Structure-Activity Relationship Analysis to Evaluate Human ATP-Binding Cassette Transporter ABCG2-Drug Interactions
- H. Saito, H. Hirano, +12 authors Toshihisa Ishikawa
- Chemistry, Medicine
- Journal of Pharmacology and Experimental…
- 1 June 2006
The human ATP-binding cassette (ABC) transporter ABCG2 (BCRP/MXR1/ABCP) plays a critical role in cellular protection against xenobiotics as well as pharmacokinetics of drugs in our body. In the… Expand
Reducing Wrong Labels in Distant Supervision for Relation Extraction
We propose a generative model that directly models the heuristic labeling process of distant supervision. Expand