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Targeting superoxide dismutase to renal proximal tubule cells inhibits mitochondrial injury and renal dysfunction inuduced by cisplatin.
- M. Nishikawa, H. Nagatomi, B. Chang, E. Sato, M. Inoue
- Biology, ChemistryArchives of biochemistry and biophysics
- 1 March 2001
The results suggest that targeting SOD to proximal tubule cells protects renal function and permits the administration of fairly high doses of nephrotoxic anticancer agents, such as cisplatin, without causing renal injury.
THE USE OF DIFFUSION CHAMBERS IN INVESTIGATING THE CELLULAR NATURE OF IMMUNITY IN EXPERIMENTAL TYPHOID AND TUBERCULOSIS.
Targeting superoxide dismutase to renal proximal tubule cells inhibits nephrotoxicity of cisplatin and increases the survival of cancer-bearing mice.
Study of Bacteriophages in Kinko Bay
The authors found that in order to isolate the phage from sea water, the enrichment of phages before isolation is indispensable and all bacteriophages isolated demonstrated strong resistance to various agents; i.e., to chemicals, to hypotonic solutions such as diluted artificial sea water.
[PASSIVE TRANSFER OF IMMUNITY TO TUBERCULOSIS BY MEANS OF CELLS FROM BCG VACCINATED MICE. II. EFFECTS OF VARIOUS PRETREATMENTS OF CELLS TO BE TRANSFERRED].
Studies on the anti-inflammatory activity and ulcerogenic adverse effect of thiazole derivatives, especially 2-amino-thiazoleacetic acid derivatives.
A series of derivatives of 4-arylthiazole acetic acid and 2-aminothiazole were studied with respect of their antiinflammatory effect in rat carrageenin edema, and two compounds gave the preferable results with almost no gastric damage at the higher dosage together with its good anti-edematous activity.
[Clinical characteristics of the lung diseases due to Mycobacterium avium and Mycobacterium intracellulare classified by DNA probe test].
Between M. avium and M. intracellulare, there was no significant differences in the samples' backgrounds and the clinical characteristics except for their prognoses, and no remarkable difference was found in the susceptibility to other antituberculous drugs.
[TRANSFER OF IMMUNITY TO TUBERCULOSIS BY MEANS OF CELLS FROM BCG VACCINATED MICE. 1. ON THE EFFECT OF TRANSFERRED CELLS IN 2 MOUSE STRAINS DIFFERING IN SUSCEPTIBILITY TO TUBERCULOSIS].
[Identification and sero-typing of the clinically isolated atypical mycobacterium strains (author's transl)].
Antigen-Binding Activity and Allergenicity of Heterologous γ-Globulin Absorbed from the Rectum
The molecular integrity of rectally absorbed antigens was studied in rats and mice. About 2% in the radioactivity of 125I-labelled horse γ -globulin administered rectally