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Mammalian protein metabolism
  • 3,073
  • 24
Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.
The mRNAs for the heavy and light subunits of the iron-storage protein ferritin occur in cells largely as inactive ribonucleoprotein particles, which are recruited for translation when iron entersExpand
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Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
The effect of dietary protein content on the diurnal variations in plasma neutral amino acid levels was studied in normal human subjects. For three consecutive 5-day periods, subjects consumed dietsExpand
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The determination of nucleic acids.
  • H. Munro
  • Chemistry, Medicine
  • Methods of biochemical analysis
  • 31 October 2006
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Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron.
Synthesis of the iron-storage protein ferritin is thought to be regulated at the translational level by the cytosolic content of chelatable iron. This response to iron is regulated by theExpand
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Ntau-methylhistidine (3-methylhistidine) and muscle protein turnover: an overview.
Actin and myosin, the contractile proteins of skeletal muscle, are methylated following peptide bond synthesis, with production of Ntau-methylhistidine (3-methylhistidine, 3-MeHis). DuringExpand
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Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1.
Interleukin-1 (IL-1 beta) increases the synthesis of both heavy and light (L)-ferritin subunits when added to human hepatoma cells (HepG2) grown in culture. RNase protection and Northern blotExpand
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Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.
  • N. Aziz, H. Munro
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 December 1987
In previous studies, we showed that acute administration of iron to intact rats or to rat hepatoma cells in culture induces synthesis of the iron-storage protein ferritin by activating translation ofExpand
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Whole-body leucine and lysine metabolism: response to dietary protein intake in young men.
Whole-body leucine and lysine metabolism was explored in young adult men by a primed constant intravenous infusion of a mixture of L-[1-13C]leucine and L-[alpha-15N]lysine over a 4-h period. SubjectsExpand
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