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Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl‐2 and Bcl‐xL genes
To determine whether a specifically designed bispecific (Bcl‐2/Bcl‐xL) antisense oligonucleotide (ASO) induces apoptosis and enhances chemosensitivity in human prostate cancer LNCaP cells, as Bcl‐2… Expand
The significance of lymphadenectomy in transitional cell carcinoma of the upper urinary tract.
- H. Miyake, I. Hara, K. Gohji, S. Arakawa, S. Kamidono
- British journal of urology
- 1 October 1998
OBJECTIVE To determine the efficacy of lymphadenectomy after nephroureterectomy in patients with transitional cell carcinoma (TCC) of the upper urinary tract. PATIENTS AND METHODS Between January… Expand
Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade.
PURPOSE Large meta-analyses have documented that maximum androgen blockade with nonsteroidal antiandrogens for advanced prostate cancer confers survival benefits, although it remains controversial.… Expand
Expression profile of E-cadherin and N-cadherin in non-muscle-invasive bladder cancer as a novel predictor of intravesical recurrence following transurethral resection.
- M. Muramaki, H. Miyake, T. Terakawa, Masafumi Kumano, I. Sakai, M. Fujisawa
- Urologic oncology
- 1 March 2012
The objective of this study was to investigate the impact of the expression profile of E-cadherin and N-cadherin in newly diagnosed non-muscle-invasive bladder cancer (NMIBC) on the probability of… Expand
Gender as a significant predictor of intravesical recurrence in patients with urothelial carcinoma of the upper urinary tract following nephroureterectomy.
- Y. Kusuda, H. Miyake, T. Terakawa, Y. Kondo, T. Miura, M. Fujisawa
- Urologic oncology
- 1 August 2013
OBJECTIVES To retrospectively assess the significance of gender as a predictor of intravesical recurrence following nephroureterectomy for urothelial carcinoma of the upper urinary tract (UC-UUT). … Expand
Expression of potential molecular markers in renal cell carcinoma: impact on clinicopathological outcomes in patients undergoing radical nephrectomy
To evaluate the expression levels of several potential molecular markers in renal cell carcinoma (RCC), to clarify the significance of these markers as prognostic predictors in patients undergoing… Expand
Elevation of serum levels of urokinase‐type plasminogen activator and its receptor is associated with disease progression and prognosis in patients with prostate cancer
Several investigators have revealed that urokinase‐type plasminogen activator (uPA) and its receptor (uPAR) are overexpressed in serum as well as in tumor tissues in patients with various types of… Expand
Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer
The discovery and targeting of genes mediating androgen-independence may lead to the development of novel therapies that delay progression of hormone refractory prostate cancer (HRPC). Clusterin is a… Expand
Increased angiogenin expression in the tumor tissue and serum of urothelial carcinoma patients is related to disease progression and recurrence
The progression of solid tumors is at least partly dependent on angiogenesis, the induction of which is mediated by several angiogenic factors, including angiogenin (ANG). The authors evaluated the… Expand
Computed diffusion-weighted imaging using 3-T magnetic resonance imaging for prostate cancer diagnosis
ObjectiveTo assess the efficacy of computed diffusion-weighted images (cDWIs) of b = 2000 s/mm2 (cDWI2000) generated from DWIs of b = 0 and 1000 for prostate cancer (PCa) diagnosis in comparison with… Expand