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Cell culture assay system for the evaluation of natural product-mediated anti-Hepatitis B virus activity.
Utilizing the hepatitis B virus (HBV)-producing hepatoblastoma cell line, HepG2.2.15, which is stably transfected with the cloned HBV genome, methods were devised to examine the effects of testExpand
Hepatoprotective activity of kutkin--the iridoid glycoside mixture of Picrorhiza kurrooa.
Changes in the lipid composition and activities of isocitrate dehydrogenase and isocitrate lyase during encystation of Acanthamoeba culbertsoni strain A-1.
  • H. Mehdi, N. Garg
  • Biology, Medicine
  • Transactions of the Royal Society of Tropical…
  • 1 July 1987
The contents of total lipids, total sterols, total and individual phospholipids were significantly lower in mature cysts of Acanthamoeba culbertsoni strain A-1 than in trophozoites while the radioactivity increased in the akali-insoluble fraction (cellulose). Expand
Effect of cholesterol and alpha-p-chlorophenoxyisobutyrate passage on virulence in Acanthamoeba culbertsoni strain A-1 and C-7.
Effect of cholesterol and α - p -chlorophenoxyisobutyrate passage on virulence in Acanthamoeba culbertsoni strain A-1 and C-7 and passage through cholesterol caused gradual induction of invasiveness, stimulation of multiplication, increase in sterol andospholipid contents and phospholipase A activity of the trophozoites. Expand
Sterols of Acanthamoeba culbertsoni strain A-1
Two new sterols have been characterized along with ergosterol and 7-dehydrostigmasterol in the nonsaponifiable fraction of the total lipids extracted from trophozoites of Acanthamoeba culbertsoni strain A-1 (virulent strain). Expand
Increase in activity and biosynthesis of phospholipase A of Entamoeba histolytica by cholesterol passage.
Incorporation of 14 C ammo acids into the proteins at various stages of enzyme purification suggests that cholesterol passage increased the synthesis and activity of phospholipase A in the trophozoites. Expand
In vitro models of human disease states
Publisher Summary This chapter focuses on the treatment of most systemic diseases that involves the administration of drugs and it is apparent that drug-based therapeutic strategies will predominateExpand
Studies on lipid metabolism in amoebae