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Biomarkers of Nutrition for Development-Folate Review.
The Biomarkers of Nutrition for Development (BOND) project is designed to provide evidence-based advice to anyone with an interest in the role of nutrition in health. Specifically, the BOND programExpand
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Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.
A modestly elevated total plasma homocysteine concentration (tHcy) is generally accepted as an independent and graded risk factor for various pathologies, including vascular diseases, neural tubeExpand
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Folate bioavailability.
The achievement of optimal folate status to prevent neural-tube defects, and possibly other diseases, is hindered by the well-recognised incomplete bioavailability of the natural folates found inExpand
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Intake and status of folate and related B-vitamins: considerations and challenges in achieving optimal status.
Folate and the metabolically related B-vitamins, vitamin B12 and riboflavin, have attracted much scientific and public health interest in recent years. Apart from a well established role inExpand
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Homocysteine, B-vitamins and CVD.
There is considerable interest in plasma homocysteine (tHcy) as a CVD risk factor. Although the secondary prevention trials published to date have been inconclusive in confirming a benefit ofExpand
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Effect of a voluntary food fortification policy on folate, related B vitamin status, and homocysteine in healthy adults.
BACKGROUND Mandatory folic acid fortification of food is effective in reducing neural tube defects and may even reduce stroke-related mortality, but it remains controversial because of concerns aboutExpand
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Nutrient intakes and impact of fortified breakfast cereals in schoolchildren.
OBJECTIVE: To report micronutrient intakes in Northern Ireland schoolchildren, and to establish the contribution of fortified breakfast cereal to overall nutrient intakes and achievement of currentExpand
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Studies of biomarker responses to intervention with vitamin B-12: a systematic review of randomized controlled trials.
BACKGROUND Mild vitamin B-12 deficiency is common among older adults, but evidence for setting dietary recommendations is limited because most studies have administered vitamin B-12 via nonoralExpand
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Effect of increasing dietary folate on red-cell folate: implications for prevention of neural tube defects
BACKGROUND Recommendations by the UK Department of Health suggest that protection from neural tube defects (NTD) can be achieved through intakes of an extra 400 microgram daily of folate/folic acidExpand
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Plasma homocysteine, a risk factor for cardiovascular disease, is lowered by physiological doses of folic acid.
Elevated plasma homocysteine, an independent risk factor for cardiovascular disease (CVD) can be lowered by administration of pharmacological doses of folic acid. The effect of lower doses inExpand
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