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MRI of the lungs using hyperpolarized noble gases
The nuclear spin polarization of the noble gas isotopes 3He and 129Xe can be increased using optical pumping methods by four to five orders of magnitude. This extraordinary gain in polarizationExpand
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Cortical lamina-dependent blood volume changes in human brain at 7T
Cortical layer-dependent high (sub-millimeter) resolution functional magnetic resonance imaging (fMRI) in human or animal brain can be used to address questions regarding the functioning of corticalExpand
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Combined Evaluation of FDG-PET and MRI Improves Detection and Differentiation of Dementia
Introduction Various biomarkers have been reported in recent literature regarding imaging abnormalities in different types of dementia. These biomarkers have helped to significantly improve earlyExpand
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Sex-Dependent Influences of Obesity on Cerebral White Matter Investigated by Diffusion-Tensor Imaging
Several studies have shown that obesity is associated with changes in human brain function and structure. Since women are more susceptible to obesity than men, it seems plausible that neuralExpand
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Investigating Structural Brain Changes of Dehydration Using Voxel-Based Morphometry
Dehydration can affect the volume of brain structures, which might imply a confound in volumetric and morphometric studies of normal or diseased brain. Six young, healthy volunteers were repeatedlyExpand
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Neurocognitive functioning in adults with phenylketonuria: results of a long term study.
OBJECTIVES A controlled long-term study was performed to assess the neurological and neuropsychological performance in adult patients with early-treated phenylketonuria (PKU). METHODS WeExpand
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Individual blood–brain barrier phenylalanine transport determines clinical outcome in phenylketonuria
Different clinical outcomes in spite of comparable dietary controls are well known in patients with phenylketonuria. Currently, reasons for this phenomenon are unknown. Kinetic investigations in 15Expand
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Quantifying the intra‐ and extravascular contributions to spin‐echo fMRI at 3 T
Functional MRI (fMRI) by means of spin‐echo (SE) techniques provides an interesting alternative to gradient‐echo methods because the contrast is based primarily on dynamic averaging associated withExpand
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Whole-brain mapping of venous vessel size in humans using the hypercapnia-induced BOLD effect
Measuring the morphology of the cerebral microvasculature by vessel-size imaging (VSI) is a promising approach for clinical applications, such as the characterization of tumor angiogenesis andExpand
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Detection of emphysema in rat lungs by using magnetic resonance measurements of 3He diffusion.
Emphysema is a pulmonary disease characterized by alveolar wall destruction, resulting in enlargement of gas exchange spaces without fibrosis. This condition is a part of chronic obstructiveExpand
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