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TRPA1-Dependent Pruritus in IL-13–Induced Chronic Atopic Dermatitis
Chronic debilitating pruritus is a cardinal feature of atopic dermatitis (AD). Little is known about the underlying mechanisms. Antihistamines lack efficacy in treating itch in AD, suggesting the… Expand
Diversity of TH cytokine profiles in patients with chronic rhinosinusitis: A multicenter study in Europe, Asia, and Oceania.
- X. Wang, N. Zhang, +6 authors C. Bachert
- The Journal of allergy and clinical immunology
- 1 November 2016
BACKGROUND To date, no study has evaluated the diversity of TH cell cytokine patterns of patients with chronic rhinosinusitis (CRS) among centers in different continents using identical methods. … Expand
A Randomized Controlled Trial to Assess Adherence to Allergic Rhinitis Treatment following a Daily Short Message Service (SMS) via the Mobile Phone
Background: Short message service (SMS) has been suggested as an effective method to improve adherence to medical therapy in some chronic diseases. However, data on the effects of SMS interventions… Expand
Predictive Significance of Tissue Eosinophilia for Nasal Polyp Recurrence in the Chinese Population
- H. Lou, Yifan Meng, Y. Piao, C. Wang, L. Zhang, C. Bachert
- American journal of rhinology & allergy
- 1 September 2015
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) remains a challenging clinical entity with its propensity for recurrence. Tissue eosinophilia is a hallmark of CRSwNP, and its role in… Expand
Cellular phenotyping of chronic rhinosinusitis with nasal polyps.
BACKGROUND Defining the phenotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) with prognosis may lead to delivery of personalized treatment. This study aimed to identify cellular phenotypes… Expand
Comparison of Long-term Efficacy of Subcutaneous Immunotherapy in Pediatric and Adult Patients With Allergic Rhinitis
- Yanran Huang, C. Wang, Feifei Cao, Yan Zhao, H. Lou, L. Zhang
- Allergy, asthma & immunology research
- 8 October 2018
Purpose Data comparing the long-term efficacy and safety of subcutaneous immunotherapy (SCIT) using house dust mite (HDM) in children and adults with allergic rhinitis (AR) are limited. This study… Expand
Origin site‐based staging system of sinonasal inverted papilloma for application to endoscopic sinus surgery
We aimed to assess the recurrence risk of sinonasal inverted papillomas (SNIPs), based on a staging system developed according to the originating site of SNIP.
An increased prevalence of self‐reported allergic rhinitis in major Chinese cities from 2005 to 2011
The prevalence of allergic rhinitis (AR) has increased worldwide in recent decades. This study was conducted to investigate the prevalence of self‐reported AR and profiles of AR‐related comorbidities… Expand
Expression of IL-22 in the Skin Causes Th2-Biased Immunity, Epidermal Barrier Dysfunction, and Pruritus via Stimulating Epithelial Th2 Cytokines and the GRP Pathway
Increased expression of Th22 cytokine IL-22 is a characteristic finding in atopic dermatitis (AD). However, the specific role of IL-22 in the pathogenesis of AD in vivo has yet to be elucidated.… Expand
T cell subsets in cord blood are influenced by maternal allergy and associated with atopic dermatitis
- Yujing Fu, H. Lou, +4 authors L. Zhang
- Pediatric allergy and immunology : official…
- 1 March 2013
This study aimed to investigate the influence of maternal allergy on cord blood regulatory and effector T cells and to evaluate their role as a predictor of atopic dermatitis (AD) during the first 2… Expand