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Distribution of Circumferential Stress in Ruptured and Stable Atherosclerotic Lesions A Structural Analysis With Histopathological Correlation
Background. Although rupture of an atherosclerotic plaque is considered to be the cause of most acute coronary syndromes, the mechanism of plaque rupture is controversial. Methods and Results. ToExpand
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Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels.
It is likely that factors other than stenosis severity predispose some atherosclerotic plaques to rupture. Because focal increases in circumferential stress may be an important mechanism of plaqueExpand
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Static circumferential tangential modulus of human atherosclerotic tissue.
The mechanical properties of atherosclerotic plaque may be of critical importance to the processes of plaque rupture, the most common antecedent of myocardial infarction. To investigate the effectsExpand
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Mechanical properties of model atherosclerotic lesion lipid pools.
Structural analysis of atherosclerotic coronary arteries has suggested that stress concentrations are associated with plaque rupture and that these stress concentrations are critically dependent onExpand
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Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study.
Intravascular ultrasound may be useful for studying the natural history of atherosclerotic lesions of different morphologies and for guiding interventional strategies. This study was designed to testExpand
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Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture.
Atherosclerotic plaque rupture may occur when regions of weakened extracellular matrix are subjected to increased mechanical stresses. Since collagen is a major determinant of extracellular matrixExpand
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Computational structural analysis based on intravascular ultrasound imaging before in vitro angioplasty: prediction of plaque fracture locations.
OBJECTIVES This in vitro study was designed to test the hypothesis that a structural analysis based on intravascular ultrasound images of atherosclerotic vessels obtained before angioplasty can beExpand
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Turbulent pressure fluctuations on surface of model vascular stenoses.
Turbulence frequently develops when blood passes through a stenosis. To study the hypothesis that turbulence near a plaque surface can cause pressure fluctuations that may promote plaque rupture,Expand
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A freeze-drying process for fabrication of polymeric bridges for peripheral nerve regeneration
The goal of this research is a manufacturing technique for biodegradable collagenglycosaminoglycan (CG) polymers with controlled pore structure. When used to bridge a 15-mm gap in the rat sciaticExpand
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High stress regions in saphenous vein bypass graft atherosclerotic lesions.
OBJECTIVES Our aim was to test the hypothesis that maximal stresses in saphenous vein atherosclerotic stenoses are greater than those in native coronary artery stenoses. BACKGROUND The patency ofExpand
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