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Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382
BACKGROUND Consistent long-term viral suppression has been difficult to achieve in children with human immunodeficiency virus type 1 (HIV-1) infection. We tested the safety and antiviral efficacy ofExpand
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Detection of human immunodeficiency virus type 1 provirus in mononuclear cells by in situ polymerase chain reaction.
BACKGROUND Studies of human immunodeficiency virus type 1 (HIV-1) infection have attempted to quantitate the viral load correlate it with the degree of immune deficiency. In one study, only about 1Expand
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Effects of alcohol ingestion on in vitro susceptibility of peripheral blood mononuclear cells to infection with HIV and of selected T-cell functions.
A role for the biological effects of alcohol is postulated in the increased risk of AIDS known to be associated with chronic alcohol abuse and alcohol consumption during sexual activity. In pilotExpand
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Possible graft-versus-host reaction after intrauterine transfusion for Rh erythroblastosis fetalis.
Abstract An illness characterized by jaundice, aplastic anemia and striking histiocytic reaction in the bone marrow developed in an eight-week-old infant who survived three intrauterine transfusionsExpand
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Angiocentric CD3+ T-Cell Infiltrates in Human Immunodeficiency Virus Type 1-Associated Central Nervous System Disease in Children
ABSTRACT A significant proportion of brain tissue specimens from children with AIDS show evidence of vascular inflammation in the form of transmural and/or perivascular mononuclear-cell infiltratesExpand
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A newly recognized cause of wheezing: AIDS‐related bronchial leiomyomas
We present two human immunodeficiency virus‐infected children who developed wheezing and radiological evidence of pulmonary air trapping due to intra‐ and peribronchial leiomyomas. At autopsy,Expand
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Chronic pulmonary complications of early influenza virus infection in children.
In 3 male patients, chronic pulmonary sequelae followed influenza virus infection at 5, 24, and 42 months of age. Varying degrees of interstitial fibrosis, bronchial and bronchiolar erosions andExpand
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Activity of dextran sulfate and other polyanionic polysaccharides against human immunodeficiency virus.
Human immunodeficiency virus type 1 (HIV-1) is tropic for human T helper/inducer lymphocyte subsets, a finding shown by reactivity with monoclonal antibodies (MAbs) specific for CD4 (T4) molecules.Expand
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Cytokine patterns during progression to AIDS in children with perinatal HIV infection.
Patterns of cytokine expression were analyzed in polyclonal and antigenic responses in children with perinatal HIV infection. Responses of PBL to PMA and A23187 calcium ionophore studied in patientsExpand
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