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Solid stress inhibits the growth of multicellular tumor spheroids
In normal tissues, the processes of growth, remodeling, and morphogenesis are tightly regulated by the stress field; conversely, stress may be generated by these processes. We demonstrate that solidExpand
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Differential hERG ion channel activity of ultrasmall gold nanoparticles
Understanding the mechanism of toxicity of nanomaterials remains a challenge with respect to both mechanisms involved and product regulation. Here we show toxicity of ultrasmall gold nanoparticlesExpand
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Isolation of human antibodies to tumor-associated endothelial cell markers by in vitro human endothelial cell selection with phage display libraries.
Human antibodies selectively targeting angiogenic vessels hold great promise for the immunotherapy of human malignancies and can help to elucidate the molecular mechanisms regulating angiogenesis. ByExpand
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Functional significance of hsp90 complexes with NOS and sGC in endothelial cells.
Although the existence of hsp90-NOS and hsp90-sGC complexes is now firmly established, their role in many pathophysiological processes remain unclear. These complexes may represent physiologicalExpand
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Tumor cell spheroids induce a mitogenic response in endothelial cells.
Conditioned media from spheroids of human colorectal tumor cell lines HT29, SW620, SW480 and CaCo-2 were tested for their mitogenic activity on human umbilical vein endothelial (HUVE) and bovineExpand
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Angiogenic potential of malignant and non‐malignant human breast tissues in an in vivo angiogenesis model
Tumors need to acquire an angiogenic phenotype for outgrowth and metastasis formation. Limited information on the angiogenic potential of specific tissues, especially human breast tissues isExpand
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Towards nanotechnology regulation — Publish the unpublishable
Summary In an ideal world, regulation should seek to facilitate and harmonize the identification, characterization and control of all hazards, exposures and risks associated with substances andExpand
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Pulmonary injury associated with spray of a water-based nano-sized waterproofing product: a case study
BackgroundIn most reported cases of lung trauma with water proofing products, volatile organic compounds (VOC) have a prominent role. Here we report on a case involving ten workers exposed to aExpand
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P293 Pulmonary injury associated with a spray application of a water-based waterproofing product
Ten workers suffered from respiratory complaints after spray impregnation of hardwood furniture with a waterproofing product that contained a fluorinated acrylate copolymer in an aqueous suspension.Expand
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