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ROBO4 Variants Predispose Individuals to Bicuspid Aortic Valve and Thoracic Aortic Aneurysm
The identification of variants in ROBO4 (which encodes a factor known to contribute to endothelial performance) that segregate with disease in two families are reported, identifying a novel endothelial etiology for this common human disease phenotype.
Better than fish on land? Hearing across metamorphosis in salamanders
- C. B. Christensen, H. Lauridsen, J. Christensen-Dalsgaard, M. Pedersen, P. Madsen
- Environmental ScienceProceedings of the Royal Society B: Biological…
- 7 March 2015
It is shown that air-induced pressure detection enhances underwater hearing sensitivity of salamanders at frequencies above 120 Hz, and that both terrestrial adults and fully aquatic juvenile salamander can detect airborne sound.
Inside Out: Modern Imaging Techniques to Reveal Animal Anatomy
This methodological review presents the experiences of biologists using MRI, CT and μCT to create advanced representation of animal anatomy, including bones, inner organs and blood vessels in a variety of animals, including fish, amphibians, reptiles, mammals, and spiders.
The chinchilla as a novel animal model of pregnancy
- Emmeli F R Mikkelsen, H. Lauridsen, M. Pedersen
- Medicine, BiologyRoyal Society Open Science
- 1 April 2017
This proof-of-concept study demonstrated the feasibility in laboratory settings, and demonstrated the potential of the pregnant chinchilla as an animal model for obstetric research and its potential usefulness for non-invasive measurements in the placenta.
High-resolution ex vivo magnetic resonance angiography: a feasibility study on biological and medical tissues
Ex vivo MR angiography provided detailed information similar to or better than conventional CTA in its ability to visualize vessel configuration while avoiding interfering signals from adjacent bones and it was found that vascular tissue becomes leaky when formalin-fixed, leading to increased permeability and extravascular leakage of MR contrast agent.
Morphology and Function of the Lymphatic Vasculature in Patients With a Fontan Circulation
The results indicate a challenged lymphatic vasculature in the Fontan circulation and may play a role in the pathogenesis of the complications that are seen in Fontan patients.
Cardiovascular anatomy and cardiac function in the air-breathing swamp eel (Monopterus albus).
MR angiography demonstrates a positive correlation between placental blood vessel volume and fetal size
- A. S. Rasmussen, E. Stæhr-Hansen, H. Lauridsen, N. Uldbjerg, M. Pedersen
- Medicine, BiologyArchives of Gynecology and Obstetrics
- 18 July 2014
Interestingly, a positive correlation between FPBV and fetal size is found, and whether MRI angiography (without gadolinium-containing agents) is suitable as a novel diagnostic modality for placental dysfunction is investigated.
From tissue to silicon to plastic: three-dimensional printing in comparative anatomy and physiology
- H. Lauridsen, Kasper Hansen, Mathias Ørum Nørgård, Tobias Wang, M. Pedersen
- BiologyRoyal Society Open Science
- 1 March 2016
This communication reports how computed tomography and magnetic resonance imaging are applied to produce digital models of animal anatomy well suited to be printed on low-cost 3D printers, and seeks to inspire fellow researchers in these fields to embrace this emerging technology.
Ultrasound imaging of the anterior section of the eye of five different snake species
Measurements of the structures in the anterior segment of the eye can serve as orientative values for snakes examined for ocular diseases and it is demonstrated that using a high frequency transducer minimizes the risk of misinterpreting artifacts as ocular structures.