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In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones.
A series of monomeric and dimeric naphthoquinones with potential for treatment of Leishmania infections was identified in vitro using both a direct cytotoxicity assay against extracellularExpand
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New butenolides from two marine streptomycetes.
Chemical examination of two marine Streptomycetes has resulted in the isolation of four new butenolides, namely 4, 10-dihydroxy-10-methyl-dodec-2-en-1,4-olide (1), two diastereomericExpand
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Butyl-meta-cycloheptylprodiginine--a revision of the structure of the former ortho-isomer.
A red pigment produced by the actinomycete strain B 4358 was identified as butyl-meta-cycloheptylprodiginine (4) by 1H, 13C and correlation via long range coupling NMR spectra. It shows strikingExpand
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Structure-activity relationships of phenyl- and benzoylpyrroles.
Antitumor, antimicrobial, and phytotoxic activities of the marine antibiotic pentabromopseudilin (1a) and related phenyl-, benzyl- and benzoyl pyrroles were compared. All activities depended stronglyExpand
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In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones.
A series of monomeric and dimeric naphthoquinones with potential for treatment of Leishmania infections was identified in vitro using both a direct cytotoxicity assay against extracellularExpand
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Prefluostatin and New Urauchimycin Derivatives Produced by Streptomycete Isolates
Abstract Guided by chemical screening, two new members of the antimycin group, urauchimycin C (1b) and D (1a), were isolated from the marine-derived Streptomyces sp. isolate B1751 and from aExpand
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Demethyl mutactimycins, new anthracycline antibiotics from Nocardia and Streptomyces strains.
New anthracycline antibiotics 3'-O-demethyl mutactimycin (3) and 4-O,3'-O-didemethyl mutactimycin (4) were isolated from two actinomycetes strains, Nocardia transvalensis and Streptomyces sp. GWExpand
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Niruriflavone, a New Antioxidant Flavone Sulfonic Acid from Phyllanthus niruri
A new flavone sulfonic acid 1 named niruriflavone was isolated from the 70% ethanolic extract of the whole plant of Phyllanthus niruri (Euphorbiaceae), together with 6,10,14-trimethyl-2-Expand
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The separation of hypericine and pseudohypericine from Hypericum perforatum L.
The extraction of Hypericum perforatum L. was carried out by the method of ultrasonic maceration. The separation of H. perforatum L. extract in order to obtain hypericine and pseudohypericine richExpand
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