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Slow current systems in the A-V node of the rabbit heart
TLDR
The slow inward current as well as the delayed potassium current in the A-V node is demonstrated using the two-microelectrode voltage-clamp technique.
Cause of persistent hypouricemia in outpatients.
TLDR
The results suggest that persistent hypouricemia in outpatients is of very low incidence, is usually caused by an isolated metabolic error of urate transport, and is not related to drug ingestion or systemic disease.
Slow inward current and its role mediating the chronotropic effect of epinephrine in the rabbit sinoatrfal node
TLDR
Voltage clamp experiments using the two microelectrode technique revealed the following changes in the membrane current: epinephrine increased the limiting conductance for the slow inward current (is) by approximately 30% and the potassium current (ik) by about 10%, keeping the kinetics ofis andik constant.
Renal handling of urate in two patients with hyperuricemia and primary hyperparathyroidism.
TLDR
In hyperuricemia patients with primary hyperparathyroidism, the reduction of tubular urate secretion via hypoperfusion of the capillary network is typically present, however, the severity of the hyperurcemia might be dependent on the dysfunction of the postsecretory reabsorption of urate.
Electrophysiological study of cibenzoline in voltage-clamped rabbit sinoatrial node preparations.
TLDR
The results suggest that cibenzoline exerts a depressant effect on the electrical activity of sinoatrial node cells and that the depression of the currents induced by ciberenzoline is due to a reduction in conductances of the current systems.
Delayed cardiac tamponade and hemothorax induced by an acupuncture needle.
TLDR
A 52-year-old man who presented with cardiac tamponade a few years after accidental breakage of an acupuncture needle that had not been removed showed a possible threat of 'stealthy' and migrating foreign bodies, such as very fine acupuncture needles.
Slow recovery of conduction velocity from use dependent inhibition induced by quinidine in guinea pig ventricular myocardium.
TLDR
The onset and recovery of the use dependent inhibition of conduction by antiarrhythmic drug may not always parallel the changes of the dV/dtmax of action potential in multicellular muscle preparations.
Clinical significance of hypouricemia in hospitalized patients.
TLDR
Serum uric acid was measured in 586 normal subjects and 1,220 hospitalized patients and hypouricemia was found to be relatively common in hospitalized patients, and seems to be caused mainly by medication, neoplastic diseases, liver disorders and transfusions.
The usefulness of exercise‐induced QRS axis shift as a predictor of coronary artery disease
TLDR
The QRS axis of 101 patients with coronary artery disease (CAD) and 57 normal subjects without CAD who underwent coronary arteriograms were measured before and after exercise testing and the axis shift response is no more sensitive for the detection of CAD than ST depression.
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