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Arterial stenting and balloon angioplasty in ostial atherosclerotic renovascular disease: a randomised trial
TLDR
PTAS is a better technique than PTA to achieve vessel patency in ostial atherosclerotic renal-artery stenosis, however, the burden of reintervention after PTA outweighs the potential saving in stents, so primary PTAS is the better approach to use. Expand
Hemodynamic patterns and spectral analysis of heart rate variability during dialysis hypotension.
TLDR
It is indicated that activation of the sympatho-inhibitory cardiodepressor reflex (Bezold-Jarisch reflex), which is a physiologic response to a critical reduction in intravascular volume and cardiac filling, is the cause of sudden intradialytic hypotension. Expand
Acute renal failure after allogeneic myeloablative stem cell transplantation: retrospective analysis of incidence, risk factors and survival
TLDR
This retrospectively analysed ARF in 363 recipients of allogeneic myeloablative SCT to identify incidence, risk factors, associated post-transplantation complications and mortality of ARF, showing that ARF without co-morbid conditions has a good prognosis, and ARF with co- Morbid Conditions has a poor prognosis. Expand
Sympathetic hyperactivity in chronic renal failure: a wake-up call.
TLDR
A case is made for increased application of specific adrenergic blockers in patients with CRF, because of the unwillingness to treat CRF patients with beta-blockers, even if they have had a myocardial infarction. Expand
Effects of endothelin-1 on renal function in humans: implications for physiology and pathophysiology.
TLDR
According to this study, endothelin-1 participates in volume homeostasis in human, whereas pathophysiological concentrations can contribute to renal vasoconstriction and sodium retention, and calcium channel blockers may protect against these effects of endothelins-1. Expand
Daily home haemodialysis in The Netherlands: effects on metabolic control, haemodynamics, and quality of life.
TLDR
DHHD compared to conventional thrice-weekly haemodialysis with similar weekly Kt/V results in an improved haemodynamic control and quality of life, but has lesser impact on metabolic regulation. Expand
Arterial stiffness and fetal growth in normotensive pregnancy.
TLDR
There was a significant relationship in PWV with both birth weight centiles and catch-up growth after birth, independent of mean arterial pressure, which suggests that arterial stiffness reflects maternal vascular adaptation to pregnancy better than blood pressure. Expand
Impaired renal blood flow autoregulation in two-kidney, one-clip hypertensive rats is caused by enhanced activity of nitric oxide.
TLDR
It is indicated that perfusion pressure-dependent NO release can oppose autoregulation in the kidney, and the enhanced influence of NO on pressure- dependent RBF may facilitate the preservation of renal function in the nonclipped kidney of 2K1C rats. Expand
Tetrahydrobiopterin, but Not l-Arginine, Decreases NO Synthase Uncoupling in Cells Expressing High Levels of Endothelial NO Synthase
TLDR
Sustained increases of eNOS or VEGF activity should be accompanied by concomitant supplementation of BH4, suggesting intrinsic superoxide production by eN OS. Expand
Perinatal L-Arginine and Antioxidant Supplements Reduce Adult Blood Pressure in Spontaneously Hypertensive Rats
TLDR
Perinatal supplementation of NO substrate and antioxidants results in persistent reduction of SBP and renal protection in SHR, although effects on NOx and TBARS were only transient, which suggests a critical role for perinatal pro- and antioxidant balance in programming BP later in life. Expand
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