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Streptomyces associated with a marine sponge Haliclona sp.; biosynthetic genes for secondary metabolites and products.
Terrestrial actinobacteria have served as a primary source of bioactive compounds; however, a rapid decrease in the discovery of new compounds strongly necessitates new investigational approaches.Expand
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DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters
This article introduces DoBISCUIT (Database of BIoSynthesis clusters CUrated and InTegrated), a literature-based, manually curated database of gene clusters for secondary metabolite biosynthesis. Expand
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Brasilicardin A, a new terpenoid antibiotic from pathogenic Nocardia brasiliensis: fermentation, isolation and biological activity.
A novel tricyclic diterpenoid antibiotic, brasilicardin A, was isolated from the culture broth of Nocardia brasiliensis IFM 0406. The antibiotic exhibited immunosuppressive activity in a mouse mixedExpand
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Structure determination of a siderophore peucechelin from Streptomyces peucetius
Previously, Park et al. isolated a new siderophore from Streptomyces peucetius ATCC 27952 based on information of the genome sequence and the structure of the siderophore was deduced to be a cyclicExpand
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Brasilinolide A, a new macrolide antibiotic produced by Nocardia brasiliensis: producing strain, isolation and biological activity.
A new 32-membered macrolide antibiotic, brasilinolide A was isolated from the fermentation broth of Nocardia sp. IFM 0406. The producer was identified as Nocardia brasiliensis. The antibiotic wasExpand
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Different Rifampicin Inactivation Mechanisms in Nocardia and Related Taxa
Mycolic acid‐containing bacteria inactivate rifampicin in a variety of ways such as glucosylation, ribosylation, phosphorylation and decolorization. These inactivations were found to be aExpand
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Novel siderophore, JBIR-16, isolated from Nocardia tenerifensis NBRC 101015
Nocardia is the causative microorganism of a human infection called nocardiosis. It is also known to produce a variety of compounds with antitumor,1,2 antimicrobial3,4 and immunosuppressiveExpand
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Isolation and structure determination of new siderophore albachelin from Amycolatopsis alba
A new siderophore named albachelin was isolated from iron deficient culture of Amycolatopsis alba. The planar structure of albachelin was elucidated by the combination of ESI–MS/MS experiment and NMRExpand
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