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Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents.
It is demonstrated that 1-3, and 7 have anti-inflammatory effects and 5, 6, and 12 are potential anti- inflammation and cancer chemopreventive agents. Expand
Resveratrol nanoparticle system improves dissolution properties and enhances the hepatoprotective effect of resveratrol through antioxidant and anti-inflammatory pathways.
Resveratrol (RES), a well-known antioxidant and anti-inflammatory compound, is abundant in red wine and exerts numerous pharmacological effects, including hepatoprotection and cadioprotection.Expand
Structure-activity relationship studies on chalcone derivatives. the potent inhibition of chemical mediators release.
The potent inhibitory effect of 2',5'-dihydroxy- dihydrochaclones on NO production in LPS-activated macrophages and microglial cells is proposed to be useful for the relief of septic shock. Expand
Enhancement of dissolution and antioxidant activity of kaempferol using a nanoparticle engineering process.
It is concluded that KAEN could be a low-dose alternative to KAE in health food and future clinical research because it retained potent antioxidant activity after the nanoparticle engineering process and showed better antioxidant activity than KAE dissolved in water. Expand
Biological evaluation of secondary metabolites from the roots of Myrica adenophora.
Bioassay-guided fractionation of the roots of Myrica adenophora led to isolation of 24 known compounds and hitherto unknown compounds, including three A-type proanthocyanidins [adenodimerins A-C],Expand
Potent cytotoxic lignans from Justicia procumbens and their effects on nitric oxide and tumor necrosis factor-alpha production in mouse macrophages.
A new lignan glycoside, 4-O-alpha-L-arabinopyranosyl-(1' "-->2' ')-beta-D-apiofuranosyldiphyllin (2), named procumbenoside A, and 11 known compounds were isolated from the whole plant of Justicia procumbens, showing potent cytotoxic effects against a number of cancer cells in vitro. Expand
Antioxidant prenylflavonoids from Artocarpus communis and Artocarpus elasticus
Abstract Two new prenylflavonoids, cyclogeracommunin (1) and artoflavone A (2), were isolated from the cortex of roots of Artocarpus communis. Their structures were determined by spectroscopicExpand
Effect of Artocarpus communis Extract on UVB Irradiation-Induced Oxidative Stress and Inflammation in Hairless Mice
It is concluded that ACM extract has a photoprotective effect against UVB-induced oxidative stress and inflammation due to its sunscreen property, and its topical formulations may be developed as therapeutic and/or cosmetic products in further studies. Expand
Characteristics and properties of a novel in situ method of synthesizing mesoporous TiO2 nanopowders by a simple coprecipitation process without adding surfactant
Abstract In situ synthesis of mesoporous TiO 2 nanopowders using titanium tetrachloride (TiCl 4 ) and NH 4 OH as initial materials has been successfully fabricated by a coprecipitation processExpand
Artocarpin attenuates ultraviolet B-induced skin damage in hairless mice by antioxidant and anti-inflammatory effect.
Data suggest that artocarpin can prevent skin damage from UVB irradiation-induced photodamage in hairless mice and this is likely mediated through its antioxidant and anti-inflammation mechanisms. Expand