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Polyhydroxylated alkaloids isolated from mulberry trees (Morusalba L.) and silkworms (Bombyx mori L.).
- N. Asano, T. Yamashita, K. Ryu
- Biology, MedicineJournal of agricultural and food chemistry
- 16 August 2001
New polyhydroxylated alkaloids from the root bark of Morus alba L., and 4-O-alpha-D-galactopyranosyl-calystegine B(2) and 3 beta,6 beta-dihydroxynortropane from the fruits were isolated by column chromatography using a variety of ion-exchange resins, suggesting that the silkworm has enzymes specially adapted to enable it to feed on mulberry leaves.
In vitro inhibition and intracellular enhancement of lysosomal alpha-galactosidase A activity in Fabry lymphoblasts by 1-deoxygalactonojirimycin and its derivatives.
The results suggest that more potent inhibitors act as more effective specific chemical chaperones for the mutant enzyme, and the potent competitive inhibitors of alpha-Gal A are effective specificchemical chaperone for Fabry disease.
Effects of catechins on vascular tone in rat thoracic aorta with endothelium.
N-containing sugars from Morus alba and their glycosidase inhibitory activities.
The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10
Convolutamydine A, a novel bioactive hydroxyoxindole alkaloid from marine bryozoan Amathia convoluta
Iminosugar-producing Thai medicinal plants.
Alpha-1-C-hydroxymethylfagomine (7), 3-O-beta-D-glucopyranosyl-DMDP (12), and 2,5-dideoxy-2,5-imino-D-glucitol (13) were isolated from the Thai traditional crude drug "Non tai yak" (Stemona…
Pfaffosides, nortriterpenoid saponins, from Pfaffia paniculata☆
Fagomine isomers and glycosides from Xanthocercis zambesiaca.
Extracts from the leaves and roots of Xanthocercis zambesiaca were subjected to various ion-exchange column chromatographic steps to give fagomine, which is a good inhibitor of isomaltase and certain alpha- and beta-galactosidases.
Inhibitory effects of Zingiber officinale Roscoe derived components on aldose reductase activity in vitro and in vivo.
- A. Kato, Yasuko Higuchi, I. Adachi
- Biology, ChemistryJournal of agricultural and food chemistry
- 6 September 2006
A structure-activity relationship study revealed that the applicable side alkyl chain length and the presence of a C3 OCH3 group in the aromatic ring are essential features for enzyme recognition and binding.