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Pattern of otolith dysfunction in posterior inferior cerebellar artery territory cerebellar infarction
OBJECTIVES To document otolith dysfunction in patients with posterior inferior cerebellar artery (PICA) territory cerebellar infarction. METHODS From March to October 2006, 14 consecutive patientsExpand
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A pilot study of subcutaneous decitabine in β-thalassemia intermedia.
Ineffective erythropoiesis, the hallmark of β-thalassemia, is a result of α/non-α globin chain imbalance. One strategy to redress globin-chain imbalance is to induce γ-globin gene (HBG) expression.Expand
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Recent advances in central acute vestibular syndrome of a vascular cause
  • H. Kim, Hyung Lee
  • Medicine
  • Journal of the Neurological Sciences
  • 15 October 2012
Acute vestibular syndrome (AVS) is characterized by acute onset of spontaneous prolonged vertigo (lasting days), spontaneous nystagmus, postural instability, and autonomic symptoms. Peripheral AVSExpand
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Dysarthria induced by irinotecan in a patient with colorectal cancer.
PURPOSE Successful management and subsequent prevention of a rare adverse drug reaction (ADR) associated with irinotecan chemotherapy are reported. SUMMARY A 49-year-old man with meta-static colonExpand
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Phase 2 enzyme inducer sulphoraphane blocks prostaglandin and nitric oxide synthesis in human articular chondrocytes and inhibits cartilage matrix degradation.
OBJECTIVE We explored the inhibitory effect of sulphoraphane (SFN), a potent inducer of Phase 2 enzymes, on cytokine-induced prostaglandin E(2) (PGE2) and nitric oxide (NO) production and cartilageExpand
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Ejaculatory responses are inhibited by a new chemical entity, DA-8031, in preclinical rodent models of ejaculation.
OBJECTIVE To investigate the efficacy of DA-8031, a novel compound for the treatment of premature ejaculation (PE), we performed in vivo pharmacological studies using 2 preclinical animal models,Expand
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Long-term prognosis for hearing recovery in stroke patients presenting vertigo and acute hearing loss
BACKGROUND AND PURPOSE Vertebrobasilar ischemic stroke (VBIS) can cause acute hearing loss (AHL) because the vertebrobasilar system supplies most of the auditory system including the inner ear. TheExpand
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Orthostatic hypertension: An underestimated cause of orthostatic intolerance
OBJECTIVE To investigate the frequency and mechanism of orthostatic hypertension (OHT) in patients with orthostatic intolerance. METHODS We retrospectively reviewed 1033 consecutive case series ofExpand
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Phase II randomized study of neoadjuvant metformin plus letrozole versus placebo plus letrozole for ER-positive postmenopausal breast cancer [METEOR Study].
576Background: Neoadjuvant endocrine therapy with an aromatase inhibitor has shown efficacy comparable to that of neoadjuvant chemotherapy in postmenopausal breast cancer. Pre-/Clinical data have s...
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