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Besitzt die Proinsulinverunreinigung kommerzieller Insulinpräparate Bedeutung für die Stimulierung von Insulinantikörpern?

The hypothesis that proinsulin in commercial insulin preparations is an essential stimulus for insulin antibody production is confirmed, but the extremely small concentrations of C-chain specific antibodies in human antiinsulinsulin sera don't confirm the hypothesis.
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