H. Karppanen

Publications142
h-index30
Citations3,993
Highly Influential Citations100
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Magnesium. An update on physiological, clinical and analytical aspects.
There is an increased interest in the role of magnesium ions in clinical medicine, nutrition and physiology. The characteristics of the binding of magnesium and calcium ions to various components,… Expand
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Sodium intake and hypertension.
In current diets, the level of sodium is very high, whereas that of potassium, calcium, and magnesium is low compared with the level in diets composed of unprocessed, natural foods. We present the… Expand
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Beneficial effects of a potassium- and magnesium-enriched salt alternative.
The effects on blood pressure and the development of cardiac hypertrophy of sodium chloride (regular salt) and a novel potassium-, magnesium-, and l-lysine-enriched salt alternative, which in a… Expand
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Supplementation of plant sterols and minerals benefits obese Zucker rats fed an atherogenic diet.
In most hypertensive rat models, serum total cholesterol is typically low and the cholesterol is primarily in the HDL rather than the LDL fraction. This difference from humans usually makes these… Expand
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Why and how to implement sodium, potassium, calcium, and magnesium changes in food items and diets?
The present average sodium intakes, approximately 3000–4500 mg/day in various industrialised populations, are very high, that is, 2–3-fold in comparison with the current Dietary Reference Intake… Expand
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[Histamine receptors].
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Influence of different dietary salts on the cardiovascular and renal effects of moxonidine in spontaneously hypertensive rats
Abstract The influence of common salt (NaCl) and a novel potassium-, magnesium-, and L-lysine-enriched mineral salt on the cardiovascular and renal effects of the selective imidazoline I1-receptor… Expand
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Safety assessment of common foods enriched with natural nonesterified plant sterols
Background/Objectives: To assess safety during a diet based on low-fat foods enriched with nonesterified wood-derived plant sterols and mineral nutrients related to serum phytosterol, sex hormone and… Expand
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The effect of centrally administered TRH on blood pressure, heart rate and ventilation in rat.
Different doses (3, 16, 80, 400 and 2 000 ng per rat) of TRH or alternatively saline were infused into the lateral ventricle of urethane-anaesthetized rats and blood pressure, heart rate, respiration… Expand
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Increased kidney xanthine oxidoreductase activity in salt-induced experimental hypertension.
Clinical and experimental studies have established an association between high sodium intake and arterial hypertension. The renal mechanisms resulting in impaired sodium excretion in… Expand
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