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Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition.
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The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells
TLDR
Kaempferol is proposed as a potential chemotherapeutic agent to be used alone or in combination with 5-FU to overcome colon cancer drug resistance.
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Ham22, a mini‐F mutation which is lethal to host cell and promotes recA‐dependent induction of lambdoid prophage.
TLDR
It is argued that the H1/H2 and G1/G2 polypeptides could constitute the controlled mini‐F signal enabling the coordination between cell division and F plasmid replication and the activation of the bacterial SOS pathway.
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Amino acid structure and characterization of a heterodimeric disintegrin from Vipera lebetina venom.
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Immunized camel sera and derived immunoglobulin subclasses neutralizing Androctonus australis hector scorpion toxins.
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Asteraceae Artemisia campestris and Artemisia herba-alba Essential Oils Trigger Apoptosis and Cell Cycle Arrest in Leishmania infantum Promastigotes
TLDR
It is reported, for the first time, that antileishmanial activity of both EOs was mediated by cell apoptosis induction and cell cycle arrest at the sub-G0/G1 phase, and all results showed that EOs from A. herba-alba and A. campestris plants are promising candidates as anti-Leishmania medicinal products.
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Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels
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Purification and characterization of a growth factor-like which increases capillary permeability from Vipera lebetina venom.
TLDR
An increasing capillary permeability protein (ICPP) is isolated which is devoid of arginine ester hydrolase and phospholipase A2 activities and clearly shows considerable similarity to that of vascular endothelial growth factor and platelet-derived growth factor.
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Molecular cloning and expression of a functional snake venom serine proteinase, with platelet aggregating activity, from the Cerastes cerastes viper.
TLDR
The expression of rCC-PPP in Escherichia coli system allowed, for the first time, the preparation and purification of an active protein from snake venom with platelet proaggregant and fibrinogenolytic activities.
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Phytochemical composition and antioxidant activity of medicinal plants collected from the Tunisian flora
Abstract Polyphenols, flavonoids and condensed tannins contents, as well as the antioxidant activity of the ethanolic and aqueous extracts obtained from aerial parts of 10 wild Tunisian plants, have…
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