• Publications
  • Influence
Diagnosis and Pharmacotherapy of Stable Chronic Obstructive Pulmonary Disease: The Finnish Guidelines
The Finnish Medical Society Duodecim initiated and managed the update of the Finnish national guideline for chronic obstructive pulmonary disease (COPD). The Finnish COPD guideline was revised toExpand
  • 93
  • 8
Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo.
: The beneficial actions of non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with inhibition of cyclooxygenase-2 (COX-2), whereas some of their adverse effects are associatedExpand
  • 15
  • 3
Eosinophil apoptosis as a therapeutic target in allergic asthma.
Asthma is a chronic inflammatory disease of the airways manifesting in many different phenotypes. Allergic asthma, comprising approximately half of patients with asthma, is characterized by theExpand
  • 63
  • 1
Pulmonary Pharmacology & Therapeutics
Eosinophils play a major role in asthma. One described mechanism leading to the impaired clearance of these cells from the lung is the delay in their programmed cell death (apoptosis).Expand
  • 18
  • 1
Seinäjoki Adult Asthma Study (SAAS): a protocol for a 12-year real-life follow-up study of new-onset asthma diagnosed at adult age and treated in primary and specialised care
Seinajoki Adult Asthma Study (SAAS): a protocol for a 12-year real-life follow-up study of new-onset asthma diagnosed at adult age and treated in primary and specialised care
  • 17
[Update on current care guidelines: asthma].
Asthma is an inflammatory disease of the lower airways. The typical symptoms of asthma are cough, wheezing and shortness of breath. Asthma is diagnosed based on measures of pulmonary function showingExpand
  • 16
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers
Polygenic risk scores (PRSs) have shown promise in predicting susceptibility to common diseases 1 – 3 . We estimated their added value in clinical risk prediction of five common diseases, usingExpand
  • 14
Cost-effectiveness analysis of budesonide/formoterol maintenance and reliever therapy versus fixed combination treatments for asthma in Finland*
ABSTRACT Background: Budesonide/formoterol maintenance and reliever therapy has shown its effectiveness as a treatment for moderate-to-severe asthma. Objective: To explore the cost-effectiveness ofExpand
  • 5
Cluster analysis on longitudinal data of patients with adult-onset asthma
Background Previous cluster analyses on asthma are based on cross-sectional data. Aims and objectives To identify phenotypes of adult-onset asthma by using data from baseline (diagnostic) and 12 yearExpand
  • 7