• Publications
  • Influence
Identification of a Novel Basic Helix-Loop-Helix-PAS Factor, NXF, Reveals a Sim2 Competitive, Positive Regulatory Role in Dendritic-Cytoskeleton Modulator Drebrin Gene Expression
TLDR
Drebrin has been reported to be engaged in dendritic-cytoskeleton modulation at synapses, and such a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 in the mental retardation of Down's syndrome. Expand
Interferon-γ Interferes with Transforming Growth Factor-β Signaling through Direct Interaction of YB-1 with Smad3*
TLDR
YB-1 counter-represses TGF-β-stimulated COL1A2 transcription by interfering with Smad3 bound to the upstream sequence around –265 and subsequently by interrupting the Smad 3-p300 interaction, providing a novel insight into the mechanism by which IFN-γ/YB -1 counteracts T GF-β/Smad3. Expand
Y-box-binding Protein YB-1 Mediates Transcriptional Repression of Human α2(I) Collagen Gene Expression by Interferon-γ*
TLDR
This study represents the definitive identification of the transcription factor responsible for IFN-γ-elicited inhibition of COL1A2 expression, namely YB-1. Expand
Functional Characterization of Basic Helix-Loop-Helix-PAS Type Transcription Factor NXF in Vivo
TLDR
The findings in this study suggest that the NXF gene could be induced in response to several neurodegenerative stimuli/excitations for the cell protection, and thus provide an “on demand” cell-protection system in nervous tissue. Expand
Hepatic UDP-glucuronyltransferase(s) activity toward thyroid hormones in rats: induction and effects on serum thyroid hormone levels following treatment with various enzyme inducers.
TLDR
Investigation of induction of hepatic UDP-glucuronyltransferase activity toward thyroid hormones in male Sprague-Dawley rats found no direct correlation between decrease in thyroid hormone levels and compensatory increase in TSH levels, indicating that serum T4 levels are directly affected by hUDP-GT-T4 activity. Expand
Pyrethroids: mammalian metabolism and toxicity.
  • H. Kaneko
  • Biology, Medicine
  • Journal of agricultural and food chemistry
  • 13 April 2011
TLDR
There are substantially neither significant species differences in metabolic reactions of pyrethoids nor metabolic differences among their chiral isomers except with fenvalerate, one isomer of which yields a lipophilic conjugate causing toxicity. Expand
Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3.
TLDR
YB-1 counter-represses TGF-beta-stimulated COL1A2 transcription by interfering with Smad3 bound to the upstream sequence around -265 and subsequently by interrupting the Smad2-p300 interaction, which provides a novel insight into the mechanism by which IFN-gamma/YB1 counteracts T GF-beta/Smad3. Expand
Y-box-binding protein YB-1 mediates transcriptional repression of human alpha 2(I) collagen gene expression by interferon-gamma.
TLDR
This study represents the definitive identification of the transcription factor responsible for IFN-gamma-elicited inhibition of COL1A2 expression, namely YB-1. Expand
Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c.
TLDR
It is demonstrated, for the first time, that differential expression of IL-12p40 and IL-4 in C57BL/6 mice may be useful as a parameter for assessing influence of contact and respiratory allergens. Expand
Chapter 76 – Pyrethroid Chemistry and Metabolism
Publisher Summary Many synthetic pyrethroid insecticides, which comprise one of the major insecticide groups, are used worldwide for controlling indoor and agricultural pests. Their origin or motherExpand
...
1
2
3
4
5
...