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A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation.
BACKGROUND AND METHODS Superficial and systemic fungal infections are a major problem among severely immunocompromised patients who undergo bone marrow transplantation. We performed a double-blind,Expand
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Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide.
Fifty-one patients with acute nonlymphocytic leukemia (16 with end-stage disease, 17 in second or third remission or in early relapse, and 18 in first remission) were given infusions of HLA-identicalExpand
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Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma.
Diffuse large B-cell lymphoma (DLBCL) is characterized by a marked degree of morphologic and clinical heterogeneity. Establishment of parameters that can predict outcome could help to identifyExpand
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Evaluation of pulmonary complications after bone marrow transplantation: the role of pretransplant pulmonary function tests.
To determine whether an association exists between abnormal pulmonary function tests (PFT) before bone marrow transplantation (BMT) and the rate of pulmonary complications after BMT, weExpand
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Novel insights into the biology of myelodysplastic syndromes: excessive apoptosis and the role of cytokines.
The paradox of myelodysplastic syndromes (MDS) which present with pancytopenias despite cellular bone marrows (BM) was investigated by conducting detailed studies of proliferation and apoptosis in 89Expand
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A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow
Intravenous immunoglobulin is approved for use in allogeneic bone marrow transplant recipients for prevention of graft-versus-host disease (GVHD) and infections, but the minimally effective dose hasExpand
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Autologous bone marrow transplantation in acute leukemia: a phase I study of in vitro treatment of marrow with 4-hydroperoxycyclophosphamide to purge tumor cells.
This phase I study was conducted to determine the maximal safe concentration of 4-hydroperoxycyclophosphamide (4HC) that could be used for in vitro treatment of bone marrow from patients with acuteExpand
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Preliminary results of high-dose busulfan and cyclophosphamide with syngeneic or autologous bone marrow rescue.
The toxic effects of high-dose busulfan (16 mg/kg) and cyclophosphamide (200 mg/kg) with autologous or syngeneic bone marrow rescue were evaluated in 19 patients (11 with acute myelocytic leukemia,Expand
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Evaluation of an architecture for intelligent query and exploration of time-oriented clinical data
A two-phase, balanced cross-over study to compare efficiency and satisfaction of a group of clinicians when answering queries of variable complexity about time-oriented clinical data, typical for oncology protocols, using KNAVE-II, versus standard methods: both paper charts and a popular electronic spreadsheet. Expand
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Prevention of hypermenorrhea with leuprolide in premenopausal women undergoing bone marrow transplantation
We report on the use of leuprolide to prevent heavy menstrual bleeding that often occurs before platelet engraftment in premenopausal women undergoing bone marrow transplantation (BMT). Leuprolide, aExpand
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