• Publications
  • Influence
Heteroannulation of nitroketene N,S-arylaminoacetals with POCl3: a novel highly regioselective synthesis of unsymmetrical 2,3-substituted quinoxalines.
[reaction: see text]. A novel regioselective route for the synthesis of substituted and fused 3-chloro-2-(methylthio)quinoxalines through POCl3-mediated heteroannulation of a range ofExpand
  • 99
  • 2
Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-alpha and IL-6 inhibitors.
In the present article, we have synthesized three different series of pyrazolo[3,4-b]pyridines and their structural analogues using novel synthetic strategy involving one-pot condensation ofExpand
  • 55
  • 1
An expeditious synthesis of substituted and annelated pyrido[2,3-b]indoles
An efficient and versatile synthesis of substituted and annelated pyrido[2,3-b]indoles (α-carboline) involving conjugate displacement on α-oxoketene dithioacetals by 1-methyl-2-oxoindole enolateExpand
  • 31
  • 1
Studies on regioselective addition of benzylic organometallics to α-oxoketene dithioacetals in our aromatic annelation protocol
Abstract The α-oxoketene dithioacetals derived from various acyclic and cyclic active methylene ketones are shown to undergo either 1,2- or sequential 1,4- and 1,2-addition with various substitutedExpand
  • 24
  • 1
Efficient routes to pyrazolo[3,4-b]indoles and pyrazolo[1,5-a]benzimidazoles via palladium- and copper-catalyzed intramolecular C-C and C-N bond formation.
Efficient synthetic routes to pyrazolo[3,4-b]indoles and pyrazolo[1,5-a]benzimidazoles via intramolecular palladium- and copper-catalyzed cyclization of 1-aryl/1-unsubstitutedExpand
  • 68
Highly Diastereoselective [3+2] Cyclopenta[b]annulation of Indoles with2-Arylcyclopropyl Ketones and Diesters†
A highly diastereoselective Lewis acid (BF3·Et2O or TiCl4) induced [3+2] cycloaddition of substituted and unsubstituted indoles with 2-arylcyclopropyl ketones/diesters yielding cyclopenta[b]indolesExpand
  • 42
Regioselective synthesis of 1-aryl-3,4-substituted/annulated-5-(methylthio)pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/annulated pyrazoles.
[reaction: see text] Highly efficient and regioselective synthesis of 1-aryl-3,4-substituted/annulated-5-(methylthio)pyrazoles and 1-aryl-3-(methylthio)-4,5-substituted/annulated pyrazoles has beenExpand
  • 86
Novel Route to 2,3-Substituted Benzo[b]thiophenes via Intramolecular Radical Cyclization.
A novel route to 2,3-substituted benzo[b]thiophenes by intramolecular radical cyclization of polarized ketene dithioacetals derived from o-bromoarylacetonitriles or the correspondingExpand
  • 52
Reaction of alpha-oxoketene-N,S-arylaminoacetals with Vilsmeier reagents: an efficient route to highly functionalized quinolines and their benzo/hetero-fused analogues.
A simple, highly efficient, and regioselective synthesis of functionalized quinolines through Vilsmeier cyclization of a variety of alpha-oxoketene-N,S-anilinoacetals has been reported. TheExpand
  • 96