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Time trends in eating disorder incidence.
BACKGROUND During the years 1988-1993 the primary care incidence of anorexia nervosa in the UK remained stable, but the incidence of bulimia nervosa increased threefold. AIMS To determine whetherExpand
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Addiction rare in patients treated with narcotics.
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Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects.
We examined the relation of multivitamin intake in general, and folic acid in particular, to the risk of neural tube defects in a cohort of 23,491 women undergoing maternal serum alpha-fetoproteinExpand
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Risk of hospital admission for idiopathic venous thromboembolism among users of postmenopausal oestrogens
BACKGROUND At the request of researchers in the UK, we conducted a case-control study to explore the relation between use of postmenopausal oestrogen hormone replacement therapy (HRT) and idiopathicExpand
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Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group.
OBJECTIVE To improve understanding of the epidemiology of anaphylaxis. DATA SOURCES We performed a qualitative review by hand of the major epidemiology studies of anaphylaxis. This review wasExpand
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Statin use and cancer risk in the General Practice Research Database
In a matched case–control study using the General Practice Research Database, current statin use was not associated with a significantly altered risk of any of 13 studied cancers. UntreatedExpand
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Statins and the risk of dementia
BACKGROUND Dementia affects an estimated 10% of the population older than 65 years. Because vascular and lipid-related mechanisms are thought to have a role in the pathogenesis of Alzheimer's diseaseExpand
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Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs
Exposure to non-steroidal anti-inflammatory drugs (NSAIDs) is known to increase substantially the risk of upper gastrointestinal bleeding and perforation (UGIB). We have carried out aExpand
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Validation of information recorded on general practitioner based computerised data resource in the United Kingdom.
OBJECTIVE--To determine the extent of agreement between clinical information recorded on surgery computers of selected general practitioners and similar information in manual records of lettersExpand
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Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study
BACKGROUND Antipsychotic drugs have been associated with an increased risk of adverse events such as venous thromboembolism. Our aim was to assess this risk in users of conventional antipsychoticExpand
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