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Joint analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes
TLDR
We combined two lung cancer studies using micorarray GeneChip®, employed two gene shaving methods and a two-step survival test to identify genes with expression patterns that can distinguish diseased from normal samples, and to indicate patient survival, respectively. Expand
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Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study.
BACKGROUND Artemisinin-resistant Plasmodium falciparum has been reported in Pailin, western Cambodia, detected as a slow parasite clearance rate in vivo. Emergence of this phenotype in westernExpand
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Genome-Wide Compensatory Changes Accompany Drug- Selected Mutations in the Plasmodium falciparum crt Gene
Mutations in PfCRT (Plasmodium falciparum chloroquine-resistant transporter), particularly the substitution at amino acid position 76, confer chloroquine (CQ) resistance in P. falciparum. PointExpand
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Plasmodium falciparum Gametocyte Development 1 (Pfgdv1) and Gametocytogenesis Early Gene Identification and Commitment to Sexual Development
Malaria transmission requires the production of male and female gametocytes in the human host followed by fertilization and sporogonic development in the mosquito midgut. Although essential for theExpand
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Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum
The recent reports of artemisinin (ART) resistance in the Thai–Cambodian border area raise a serious concern on the long‐term efficacy of ARTs. To elucidate the resistance mechanisms, we performed inExpand
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Cambrian ultrapotassic rhyolites from the Lhasa terrane, south Tibet: Evidence for Andean-type magmatism along the northern active margin of Gondwana
Abstract The petrogenesis and tectonic significance of early Paleozoic magmatic rocks in south Tibet is debated. In this paper, we report Cambrian ultrapotassic felsic volcanics from the LhasaExpand
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Effects of Plasmodium falciparum mixed infections on in vitro antimalarial drug tests and genotyping.
Studying drug resistance in Plasmodium falciparum requires accurate measurement of parasite response to a drug. Factors such as mixed infection of drug-resistant and -sensitive parasites canExpand
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Metabolic Profiling of the Sink-to-Source Transition in Developing Leaves of Quaking Aspen1
Profiles of small polar metabolites from aspen (Populus tremuloides Michx.) leaves spanning the sink-to-source transition zone were compared. Approximately 25% of 250 to 300 routinely resolved peaksExpand
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Epigenetic control of the variable expression of a Plasmodium falciparum receptor protein for erythrocyte invasion
Plasmodium falciparum can invade erythrocytes by redundant receptors, some of which have variable expression. A P. falciparum clone Dd2 requiring erythrocyte sialic acid for invasion can be switchedExpand
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Functional genomics analysis of foliar condensed tannin and phenolic glycoside regulation in natural cottonwood hybrids.
Regulation of leaf condensed tannins (CT) and salicylate-derived phenolic glycosides (PG) in fast- and slow-growing cottonwood backcrosses was analyzed by metabolic profiling and cDNA microarrayExpand
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