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Correlation of Obesity and Osteoporosis: Effect of Fat Mass on the Determination of Osteoporosis
It is unclear whether fat has beneficial effects on bone, and it is anticipated that this will be an active and fruitful focus of research in the coming years. Expand
Detection of splice junctions from paired-end RNA-seq data by SpliceMap
A computational method, SpliceMap, to detect splice junctions from RNA-seq data is presented, which does not depend on any existing annotation of gene structures and is capable of finding novel splicing junctions with high sensitivity and specificity. Expand
Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases
The sex ratios in urban compared with rural cases are consistent with exposure to poultry driving the risk of infection--a higher risk in men was only recorded in urban areas but not in rural areas, and the increased risk for men was of a similar magnitude for H7N9 and H5N1. Expand
Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation
It is shown here that ISG15-deficient patients also display unanticipated cellular, immunological and clinical signs of enhanced IFN-α/β immunity, reminiscent of the Mendelian autoinflammatory interferonopathies Aicardi–Goutières syndrome and spondyloenchondrodysplasia. Expand
A GH3-like gene, CcGH3, isolated from Capsicum chinense L. fruit is regulated by auxin and ethylene*
The results implicate CcGH3 as a factor in auxin and ethylene regulation of fruit ripening and suggest that it may be a point of intersection in the signaling by these two hormones. Expand
Extensive X-linked adaptive evolution in central chimpanzees
It is concluded that most adaptive mutations are recessive in chimpanzees and this results provide an explanation for the much-discussed reduction in the human–chimpanzee divergence at the X chromosome. Expand
Diversity of the Vaginal Microbiome Correlates With Preterm Birth
It is concluded that uncultured vaginal bacteria play an important role in PTB and race/ethnicity and sampling location are important determinants of the vaginal microbiome. Expand
Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
The data suggest that HBV integration has a high potential to drive oncogenic transformation and is prone to integrate into rare fragile sites and functional genomic regions including CpG islands. Expand
Relationship between serum polyunsaturated fatty acids and pregnancy in women undergoing in vitro fertilization.
Investigation of associations between serum levels of measured PUFAs and embryo implantation in women undergoing in vitro fertilization shows that increased ω-6 to ψ-3 PUFA ratios in women undergo IVF are associated with increased implantation and pregnancy rates. Expand
Risk factors for severe illness with 2009 pandemic influenza A (H1N1) virus infection in China.
  • Hongjie Yu, Zijian Feng, +19 authors Yu Wang
  • Medicine
  • Clinical infectious diseases : an official…
  • 15 February 2011
Risk factors for severe 2009 H1N1 illness in China were similar to those observed in developed countries, but there was a lower prevalence of chronic medical conditions and a higher prevalence of obesity. Expand