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Flavonoids purified from Rhus verniciflua Stokes actively inhibit cell growth and induce apoptosis in human osteosarcoma cells.
- H. Jang, Sung-Ho Kook, +10 authors Jeong-Chae Lee
- Chemistry, Medicine
- Biochimica et biophysica acta
- 30 November 2005
Many studies have suggested that dietary flavonoids are anticancer agents that induce the apoptosis of cancer cells. However, the effects of flavonoids on the induction of apoptosis in osteosarcoma… Expand
Induction of antigen-specific systemic and mucosal immune responses by feeding animals transgenic plants expressing the antigen.
- Jong-Lye Bae, J. Lee, Tae-Jin Kang, H. Jang, Y. Jang, M. Yang
- Biology, Medicine
- 8 September 2003
A report from that the presence of lactogenic immunity in pigs protected suckling piglets from porcine epidemic diarrhea virus (PEDV) infection suggested that inducing mucosal immune responses in… Expand
Selective antiproliferative and apoptotic effects of flavonoids purified from Rhus verniciflua Stokes on normal versus transformed hepatic cell lines.
Considerable attention is being concentrated on dietary flavonoids in developing novel cancer-preventive approaches due to their potential ability to induce selective apoptosis of cancer cells. In… Expand
Demonstration of Epstein-Barr virus in odontogenic and nonodontogenic tumors by the polymerase chain reaction (PCR).
- H. Jang, J. O. Cho, C. Yoon, H. Kim, J. Park
- Medicine, Biology
- Journal of oral pathology & medicine : official…
- 1 November 2001
BACKGROUND Although considerable insight has been gamed into Epstein-Barr virus (EBV) as an important etiologic factor in various tumors, virtually little is known about the relationship between EBV… Expand
Combination therapy with BMP-2 and BMSCs enhances bone healing efficacy of PCL scaffold fabricated using the 3D plotting system in a large segmental defect model
The three-dimensional (3D) plotting system is a rapidly-developing scaffold fabrication method for bone tissue engineering. It yields a highly porous and inter-connective structure without the use of… Expand
Effect of BMP-2 Delivery Mode on Osteogenic Differentiation of Stem Cells
- Taekhee Jung, J. Lee, +9 authors Sun-Woong Kang
- Medicine, Biology
- Stem cells international
- 19 January 2017
Differentiation of stem cells is an important strategy for regeneration of defective tissue in stem cell therapy. Bone morphogenetic protein-2 (BMP-2) is a well-known osteogenic differentiation… Expand
Demineralized dentin matrix combined with recombinant human bone morphogenetic protein-2 in rabbit calvarial defects
- In-Woong Um, Suk-Hyun Hwang, +4 authors H. Jang
- Journal of the Korean Association of Oral and…
- 1 April 2016
Objectives The aim of this study was to compare the osteogenic effects of demineralized dentin matrix (DDM) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) in rabbit calvarial… Expand
The effect of carrier for BMP-2 delivery on histological aspects of tissue-engineered bone
- Sun-Young Jung, You-Jin Ko, H. Jang, Sun-Woong Kang, J. Park
- Tissue Engineering and Regenerative Medicine
- 6 November 2013
Bone morphogenetic protein-2 (BMP-2) that can regenerate bone by recruiting osteo-progenitor cells and inducing osteogenic differentiation has been highlighted as an alternative therapy to treat bone… Expand
Combination of nanoparticles with photothermal effects and phase-change material enhances the non-invasive transdermal delivery of drugs.
- Yongjin Kim, Byoungmin Kim, +4 authors Unyong Jeong
- Medicine, Chemistry
- Colloids and surfaces. B, Biointerfaces
- 1 November 2015
We describe a promising non-invasive transdermal delivery system comprising block copolymer composite micelles that contained a phase-change material (PCM), photothermal Au nanoparticles (AuNPs), and… Expand
Administration of multiple cytokine genes with anti-tumor activity inhibits both tumor incidence and tumor growth.
The finding of reporter gene expression in muscle cells after intramuscular injection of a reporter gene containing DNA has suggested that injection of a certain gene in its naked form could induce… Expand