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Antipicornavirus flavone Ro 09-0179.
Ro 09-0179 (4',5-dihydroxy-3,3',7-trimethoxyflavone), isolated from a Chinese medicinal herb, was found to have potent antiviral activity. It selectively inhibited the replication of humanExpand
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Hemolytic activity of a cyclic peptide Ro09-0198 isolated from Streptoverticillium.
Ro09-0198, a cyclic peptide isolated from culture filtrates of Streptoverticillium griseoverticillatum, induced lysis of erythrocytes. Preincubation of the peptide with phosphatidylethanolamineExpand
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Interaction of a cyclic peptide, Ro09-0198, with phosphatidylethanolamine in liposomal membranes.
Ro09-0198 is a cyclic peptide isolated from Streptoverticillium griseoverticillatum. This peptide caused permeability increase and aggregation of liposomes containing phosphatidylethanolamine.Expand
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Comparative studies on the antirhinovirus activity and the mode of action of the rhinovirus capsid binding agents, chalcone amides.
Studies of various analogs related to the antirhinovirus agent 4'-ethoxy-2'-hydroxy-4,6'-dimethoxychalcone (Chalcone Ro 09-0410) led to the identification of amide analogs that are 4.5 to 10 timesExpand
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Comparative studies on the modes of action of the antirhinovirus agents Ro 09-0410, Ro 09-0179, RMI-15,731, 4',6-dichloroflavan, and enviroxime.
Modes of action of five antirhinovirus agents were compared. Ro 09-0410, 4',6-dichloroflavan, and RMI-15,731 were active preferentially against human rhinovirus. Serotypes of the virus varied inExpand
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Comparative studies on the mechanism of action of lincomycin, streptomycin, and erythromycin.
Abstract Erythromycin inhibits translocation.Lincomycin inhibits peptide bond formation. Streptomycin inhibits translocation as well as binding of aminoacyl-tRNA.
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Release of transfer ribonucleic acid from ribosomes. A G factor and guanosine triphosphate-dependent reaction.
Abstract The heat-stable factor which was responsible for the release of tRNA from ribosomes has been identified as G factor. The release of tRNA specific for phenylalanine from 70 S ribosomes isExpand
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Release of tRNA from ribosomes by a factor other than G factor.
  • H. Ishitsuka, A. Kaji
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 May 1970
In addition to the G factor there exists another factor in the E. coli extracts which stimulates the release of tRNA from ribosomes. This factor is distinctly different from the G factor and may playExpand
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Direct and specific inactivation of rhinovirus by chalcone Ro 09-0410.
Studies of various analogs related to the antipicornavirus agent, 4',5-dihydroxy-3,3',7-trimethoxyflavone (Ro 09-0179), led to the identification of 4'-ethoxy-2'-hydroxy-4,6'-dimethoxychalcone (RoExpand
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Release of ribosome bound transfer RNA by enzymatic digestion of messenger RNA.
Abstract A factor other than G factor, which releases tRNA specific for phenylalanine (tRNAPhe) from the complex of ribosomes and polyuridylic acid has been purified and identified as eitherExpand
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