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The prognostic significance of p53 and bcl‐2 expression in lung adenocarcinoma and its correlation with ki‐67 growth fraction
The p53 and bcl‐2 gene deregulations are frequently involved in several types of epithelial malignancy. The aims of this study were to determine the relationships between the Ki‐67 labeling indexExpand
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Cost-effectiveness of ribavirin plus interferon alpha-2b for either interferon relapsers or non-responders in chronic hepatitis C: a Japanese trial.
The aim of this study was to examine the cost-effectiveness of combination therapy with ribavirin plus interferon alpha-2b compared with interferon monotherapy for hepatitis C-infected JapaneseExpand
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C-reactive protein kinetics in newborns: application of a high-sensitivity analytic method in its determination.
C-Reactive protein (CRP) is a well-known indicator of inflammation. Advances in laboratory technology have enabled its quantification at lower concentrations by an automated analyzer (1)(2)(3).Expand
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Utilization of Common Inflammatory Markers in New, Symptomatic, Primary Care Outpatients Based on Their Cost-Effectiveness
Abstract Few studies have demonstrated the optimal usage of common inflammatory markers, alone or in combination, based on the cost-effectiveness. We analyzed the yield and cost of C-reactive proteinExpand
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Common diagnostic test panels for clinical evaluation of new primary care outpatients in Japan: a cost-effectiveness evaluation.
BACKGROUND The Japan Society of Clinical Pathology (JSCP) has developed a guideline for common diagnostic test utilization in new primary care outpatients. To determine the scientific and economicExpand
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Role of inflammatory mediators in lipid A analogue (ONO‐4007)‐induced vascular permeability change in mouse skin
Endotoxin shock is accompanied by an increase in peripheral vascular permeability. It has been postulated that most biological activities of LPS are derived from lipid A moiety. Here we examined theExpand
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[Evaluation of diagnostic performance of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) for HCV related hepatocellular carcinoma developed after long-term follow up].
PURPOSE This study evaluated the diagnostic performance of two tumor markers, alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP), a combination of these tests and other common tests forExpand
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Economic consequence of immediate testing for C-reactive protein and leukocyte count in new outpatients with acute infection.
BACKGROUND There have been few well-designed studies that assess the cost-effectiveness of near-patient immediate testing. METHODS We analyzed the economic outcome of immediate testing forExpand
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Opportunistic discovery of occult disease by use of test panels in new, symptomatic primary care outpatients: yield and cost of case finding.
BACKGROUND Diagnostic test panels have been advocated by the Japan Society of Clinical Pathology for evaluation of presenting complaints of new outpatients in primary care medicine. The tests haveExpand
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Yield and cost of individual common diagnostic tests in new primary care outpatients in Japan.
BACKGROUND Appropriate diagnostic testing involves considerations of cost-effectiveness. We examined the cost-effectiveness of individual tests in a panel of tests defined by the Japan Society ofExpand
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