• Publications
  • Influence
Methods for evaluating addiction liability. (A) "Attitude" of opiate addicts toward opiate-like drugs. (B) a short-term "direct" addiction test.
A method has been developed for quantifying the "attitude" of addicts toward opiate-like drugs when administered in single or chronic dosages. Questionnaires were used which provided forExpand
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An experimental study of the etiology of rum fits and delirium tremens.
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Studies on lysergic acid diethylamide (LSD-25). I. Effects in former morphine addicts and development of tolerance during chronic intoxication.
The striking mental changes induced by the diethylamide of lysergic acid (hereafter referred to as LSD) have been studied extensively in Europe,* Great Britain,† and the United States.‡ In minuteExpand
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Comparison of psilocin with psilocybin, mescaline and LSD-25
Summary1.Reactions induced by LSD, mescaline, psilocin, and psilocybin are qualitatively similar.2.The time course of the psilocin and psilocybin reactions are shorter than those of LSD or mescalineExpand
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The effect of N,N-dimethyltryptamine in human subjects tolerant to lysergic acid diethylamide
Summary1.The spectrum of effects produced with single doses of N,N-dimethyltryptamine (DMT) in 6 nontolerant human subjects resembled those produced with lysergic acid diethylamide (LSD). Either drugExpand
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Comparison of the reactions induced by psilocybin and LSD-25 in man
  • H. Isbell
  • Psychology, Medicine
  • Psychopharmacologia
  • 2004
Summary1.The reaction induced by oral administration of 57 to 114 mcgm/kg of 0-Phosphoryl-4-hydroxy-N-dimethyltryptamine (psilocybin) has been compared with that induced by a placebo and LSD-25 (1.0Expand
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Cross tolerance between LSD and psilocybin
Summary1.In two experiments, using a cross-over design, the development of “direct” tolerance to LSD and psilocybin was measured after 10 (Experiment I) or 9 (Experiment II) volunteers had taken LSDExpand
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Actions and addiction liabilities of alpha-acetyl-methadols in man.
1. dl-, d- and l -Alpha-acetylmethadol possess addiction liability. 2. Single subcutaneous or intravenous doses of d -alpha-acetylmethadol in former morphine addicts promptly induced a train ofExpand
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Effects of (−)Δ9-trans-tetrahydrocannabinol in man
I t has long been thought tha t tetrahydrocannabinols are responsible for most of the psychological effects of hashish and marihuana (LOEW~, 1944 and 1950). WOLL~]~R, MATC]~:ETT and Lo~wF. (1942)Expand
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Cross tolerance between mescaline and LSD-25 with a comparison of the mescaline and LSD reactions
Summary1.The reactions caused by intramuscular administration of 0.75 mcg/ kg and 1.5 meg/kg of LSD-25 have been compared in the same 10 subjects with those induced by 2.5 mg/kg and 5.0 mg/kg ofExpand
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