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Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system".
C-type natriuretic peptide (CNP), the third member of the natriuretic peptide family, is thus far known to be distributed mainly in the central nervous system and is considered to act as aExpand
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Lymphocytic infundibuloneurohypophysitis as a cause of central diabetes insipidus.
BACKGROUND Central diabetes insipidus may be familial, secondary to hypothalamic or pituitary disorders, or idiopathic. Idiopathic central diabetes insipidus is characterized by selectiveExpand
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Over-expression of facilitative glucose transporter genes in human cancer.
The expression of five facilitative glucose transporter genes, GLUT1 (erythrocyte type), GLUT2 (liver type), GLUT3 (brain type), GLUT4 (muscle/fat type), and GLUT5 (small intestine type), wasExpand
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Molecular cloning of a non-isopeptide-selective human endothelin receptor.
We isolated several complementary DNA (cDNA) clones encoding a non-isopeptide-selective human endothelin receptor (ETBR) from a human placenta cDNA library. The clones, different in the length ofExpand
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Natriuretic peptides as cardiac hormones in normotensive and spontaneously hypertensive rats. The ventricle is a major site of synthesis and secretion of brain natriuretic peptide.
To study synthesis, storage, and secretion of brain natriuretic peptide (BNP) in the heart, we have measured BNP mRNA and BNP concentrations in the hearts of Wistar-Kyoto rats and also haveExpand
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The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex.
Examination of the histocompatibility region of the nonobese diabetic (NOD) mouse with antibodies against class II glycoproteins (products of immune response genes of the major histocompatibilityExpand
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Cloning and expression of human endothelin‐1 receptor cDNA
We isolated a human endothelin‐1 (ET‐1) receptor cDNA from a human placenta cDNA library. The cDNA encodes a 427‐amino acid protein with seven putative transmembrane domains. The rank order of theExpand
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Increased human brain natriuretic peptide in congestive heart failure.
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