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Comparative aspects and sex differentiation of plasma sulfamethazine elimination and metabolite formation in rats, rabbits, dwarf goats, and cattle.
- R. Witkamp, H. I. Yun, +5 authors A. van Miert
- Chemistry, Medicine
- American journal of veterinary research
- 1 October 1992
Plasma disposition and urinary recovery of sulfamethazine (SMZ), its N4-acetylated metabolite (N4AcSMZ), and 2 of its hydroxylated metabolites--5-hydroxysulfamethazine (5OHSMZ) and… Expand
Pharmacokinetics and bioavailability of cefquinome in rabbits following intravenous and intramuscular administration.
Comparative pharmacokinetic profiles of two norfloxacin formulations after oral administration in rabbits.
The pharmacokinetics and tissue distribution of two norfloxacin (NFLX) formulations, norfloxacin-glycine acetate (NFLXGA) and norfloxacin nicotinate (NFLXN), were compared after single oral… Expand
Pretreatment of male BALB/c mice with beta-ionone potentiates thioacetamide-induced hepatotoxicity.
A possible role of metabolic activation by cytochrome P450 (P450) in thioacetamide-induced hepatotoxicity was investigated in male BALB/c mice. The mice were pretreated with the P450 inducer,… Expand
Surfactin C inhibits platelet aggregation
- Sung Dae Kim, S. Park, +7 authors M. Rhee
- Chemistry, Medicine
- The Journal of pharmacy and pharmacology
- 1 June 2006
This study was designed to investigate the effect of surfactin C, which is derived from Bacillus subtilis, on platelet aggregation and homotypic leucocyte aggregation. Surfactin C strongly and… Expand
Antibacterial substance produced by Streptococcus faecium under anaerobic culture.
- S. Park, C. J. Kim, M. Uramoto, H. I. Yun, K. H. Yoon, T. Oh
- Biology, Medicine
- Bioscience, biotechnology, and biochemistry
- 23 October 1995
A facultative anaerobe isolated from Korean domestic soil produced an antibacterial substance under strict anaerobic conditions. Based on the morphological and biochemical tests, and cellular fatty… Expand
Effects of β-Glucan from Paenibacillus polymyxa and L-theanine on Growth Performance and Immunomodulation in Weanling Piglets
Forty weanling piglets (5.6±0.5 kg and 26 to 30 d of age) were used in a 28-d experiment to determine the effects of β- glucan from Paenibacillus polymyxa and L-theanine on growth performance.… Expand
Pharmacokinetics and pharmacodynamics (PK/PD) of irbesartan in Beagle dogs after oral administration at two dose rates.
- L. Carlucci, K. H. Song, H. I. Yun, H. J. Park, K. Seo, M. Giorgi
- Polish journal of veterinary sciences
- 1 September 2013
Irbesartan (Irb) is an angiotensin II type 1 receptor antagonist widely used in humans to treat hypertension. Age-related diseases such as hypertension are increasingly being diagnosed in dogs and… Expand
Influence of the injection site on the pharmacokinetics of cefquinome following intramuscular injection in piglets.
- I. B. Song, T. Kim, +5 authors H. I. Yun
- The Journal of veterinary medical science
- 31 January 2013
The aim of the present study was to investigate the influence of different injection sites, i.e., the neck area and thigh muscle, on the pharmacokinetics of cefquinome in piglets following… Expand
Developmental toxicity assessment of the new ﬂuoroquinolone antibacterial DW‐116 in rabbits
DW‐116 is a newly developed ﬂuoroquinolone antibacterial with a broad spectrum against both Gram‐positive and Gram‐negative bacteria. We have reported recently that DW‐116 is embryotoxic and… Expand