H. Hussain

Publications345
h-index34
Citations5,173
Highly Influential Citations103
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Antimicrobial Natural Products: An Update on Future Antibiotic Drug Candidates
Lapachol: An overview
Lapachol is a naphthoquinone that was first isolated by E. Paterno from Tabebuia avellanedae (Bignoniaceae) in 1882. A wide spectrum of therapeutic activities have been attributed to lapachol or its…
Screening strategies for obtaining novel, biologically active, fungal secondary metabolites from marine habitats
DETERMINATION OF MACRO AND MICRONUTRIENTS AND NUTRITIONAL PROSPECTS OF SIX VEGETABLE SPECIES OF MARDAN, PAKISTAN
This study was carried out to assess the nutritional and mineral composition of selected vegetables, which are commonly used as food in Pakistan. Abelmoschus esculentus, Solanum melongena, Cucurbita…
Lapachol and lapachone analogs: a journey of two decades of patent research(1997-2016)
TLDR
In order to get lead compounds, there needs to be a greater focus on the elucidation of the precise mechanism of action of these compounds including SAR and in vivo studies.
Three New Antimicrobial Metabolites from the Endophytic Fungus Phomopsis sp.
Two new chromones, phomochromone A and B (1 and 2), and one new natural cyclopentenone derivative, phomotenone (3), together with six known compounds, phomosines A-D (4-7),…
Chemical constituents of Klainedoxa gabonenses and Paullinia pinnata.
TLDR
Preliminary studies showed that 2-(4-hydroxy-3-5-dimethoxyphenyl)-3- hydroxymethyl-2,3-dihydro-1,4,5-trioxaphenanthren-6-one showed moderate algicidal activity against the alga Chlorella fusca.
Antimicrobial natural products: an update on future antibiotic drug candidates.
TLDR
This review will describe only those with potentially useful antimicrobial activity, viz. with MICs in the range 0.02-10 microg mL(-1); a total of 145 compounds from 13 structural classes are discussed, and over 100 references are cited.
Newbouldiaquinone A: A naphthoquinone-anthraquinone ether coupled pigment, as a potential antimicrobial and antimalarial agent from Newbouldia laevis.
The study of the chemical constituents of the roots of Newbouldia laevis (Bignoniaceae) has resulted in the isolation and characterization of a naphthoquinone-anthraquinone coupled pigment named…
Cryptosporioptide: a bioactive polyketide produced by an endophytic fungus Cryptosporiopsis sp.
TLDR
Cryptosporioptide exhibited both lipoxygenase inhibitory and anti-Bacillus megaterium activities and the absolute configuration was established by means of electronic circular dichroism (ECD).
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