• Publications
  • Influence
Three new cytotoxic cyclic acylpeptides from marine Bacillus sp.
Three new cytotoxic cyclopeptides belonging to iturin class have been isolated from marine bacterium Bacillus sp. These three compounds have the cytotoxic activities. Their structures were determined
Gracilarioside and gracilamides from the red alga Gracilaria asiatica.
TLDR
Three gracilarioside and two gracilamides with unusual cyclopropane-containing alkyl chains were isolated from the red alga Gracilaria asiatica and were mildly cytotoxic to the human A375-S2 melanoma cell line.
Two new triterpenoids from the resin of Boswellia carterii
TLDR
Two new triterpenoids, 3-oxotirucalla-7,9(11),24-trien-21-oic acid and 18Hα,3β,20β-ursanediol (2), along with 15 known triter penoids, are isolated from the resin of Boswellia carterii Birdw.
Lanostane-type triterpenoids from the roots of Kadsura coccinea.
Seven new lanostane-type triterpenoids, seco-coccinic acids A-F (1- 6) and coccinilactone A (7), were isolated from the roots of Kadsura coccinea. Their structures were established on the basis of
Identification of flavonolignans from Silybum marianum seeds as allosteric protein tyrosine phosphatase 1B inhibitors
TLDR
The potentiality of these PTP1B inhibitors as lead compounds for further drug developments is suggested, based on kinetic analyses and structure–activity relationship.
Five new 3,4-seco-lanostane-type triterpenoids with antiproliferative activity in human leukemia cells isolated from the roots of Kadsura coccinea.
TLDR
Five new 3,4-seco-lanostane-type triterpenoids, seco-coccinic acids G-K (1-5), and a known compound, Seco- coccinic F, were isolated from the roots of Kadsura coccinea and showed antiproliferative effects in human leukemia cells.
Acetyl-keto-beta-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells.
TLDR
The results suggest that AKBA induces apoptosis in prostate cancer cells through a DR5-mediated pathway, which probably involves the induced expression of CHOP.
New butenolide derivatives from the marine sponge-derived fungus Aspergillus terreus.
New Spirotetronate Antibiotics, Lobophorins H and I, from a South China Sea-Derived Streptomyces sp. 12A35
TLDR
Two new spirotetronate antibiotics, lobophorins H and I, along with three known analogues, O-β-kijanosyl-(1→17)-kijanolide (3), lobophOrins B (4) and F (5) were characterized by 1D, 2D-NMR and MS data, and exhibited significant inhibitory activities against Bacillus subtilis.
...
1
2
3
4
5
...