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Distinct Subtypes of Somatostatin-Containing Neocortical Interneurons Revealed in Transgenic Mice
GABA-releasing inhibitory interneurons in the cerebral cortex can be classified by their neurochemical content, firing patterns, or axonal targets, to name the most common criteria, but whetherExpand
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Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency.
  • M. Sausbier, H. Hu, +14 authors P. Ruth
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 22 June 2004
Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance voltage- and Ca(2+)-activated K(+) channelExpand
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Robust but delayed thalamocortical activation of dendritic-targeting inhibitory interneurons
GABA-releasing cortical interneurons are crucial for the neural transformations underlying sensory perception, providing “feedforward” inhibition that constrains the temporal window for synapticExpand
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The Localization of the Brain-Specific Inorganic Phosphate Transporter Suggests a Specific Presynaptic Role in Glutamatergic Transmission
Molecular cloning has recently identified a vertebrate brain-specific Na+-dependent inorganic phosphate transporter (BNPI). BNPI has strong sequence similarity to EAT-4, aCaenorhabditis elegansExpand
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Not all that glitters is gold: off-target recombination in the somatostatin–IRES-Cre mouse line labels a subset of fast-spiking interneurons
Neurons in the mammalian brain are a highly diverse population with a complex assortment of electrophysiological, morphological and molecular properties, which has hindered efforts to classify themExpand
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Short-Term Plasticity of Unitary Inhibitory-to-Inhibitory Synapses Depends on the Presynaptic Interneuron Subtype
Excitatory-to-inhibitory cortical synapses exhibit either short-term facilitation or depression, depending on the subtype identity of the postsynaptic interneuron, while the short-term plasticityExpand
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Submillisecond Firing Synchrony between Different Subtypes of Cortical Interneurons Connected Chemically But Not Electrically
Synchronous firing is commonly observed in the brain, but its underlying mechanisms and neurobiological meaning remain debated. Most commonly, synchrony is attributed either to electrical coupling byExpand
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Brain-Derived Neurotrophic Factor Mediates Activity-Dependent Dendritic Growth in Nonpyramidal Neocortical Interneurons in Developing Organotypic Cultures
Brain-derived neurotrophic factor (BDNF) promotes postnatal maturation of GABAergic inhibition in the cerebral and cerebellar cortices, and its expression and release are enhanced by neuronalExpand
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A Self-Quenching-Resistant Carbon-Dot Powder with Tunable Solid-State Fluorescence and Construction of Dual-Fluorescence Morphologies for White Light-Emission.
Self-quenching in the aggregation state is overcome, and tunable solid-state photoluminescence of carbon-dot powder is achieved. Furthermore, based on the controllable optical property in organicExpand
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Recruitment of GABAergic Interneurons in the Barrel Cortex during Active Tactile Behavior
Neural computation involves diverse types of GABAergic inhibitory interneurons that are integrated with excitatory (E) neurons into precisely structured circuits. To understand how each neuron typeExpand
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