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Expression and regulation of a gene encoding neural recognition molecule NB-3 of the contactin/F3 subgroup in mouse brain.
TLDR
In situ hybridization demonstrated that NB-3 mRNA was preferentially expressed in the accessory olfactory bulb, layers II/III and V of the cerebral cortex, piriform cortex, anterior thalamic nuclei, locus coeruleus of the pons and mesencephalic trigeminal nucleus, and in Purkinje cells of the cerebellum.
Differences in the Appetite-Stimulating Effect of Orexin, Neuropeptide Y and Ghrelin among Young, Adult and Old Rats
TLDR
The orexigenic effect of the peptides orexin A, NPY and ghrelin decreased in old rats, and this reduction may have been responsible for the age-related decrease in food intake.
Orexin-A does not stimulate food intake in old rats.
TLDR
Results of the present study indicate that the function of the orexin system is diminished in old rats, and the decrease in the OX1R protein level in the hypothalamus could be responsible for orexIn-A's lack of stimulation of food intake in old Rats.
Novel neural adhesion molecules in the Contactin/F3 subgroup of the immunoglobulin superfamily: isolation and characterization of cDNAs from rat brain
TLDR
Nucleotide sequence analyses have shown that NB-2 and NB-3 are comprised of 1099 and 1028 amino acid residues, respectively, and there was 51% similarity in the amino acid sequence of NB- 2 andNB-3.
Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population
TLDR
The CC type of GHSR gene polymorphism (171T/C) is a risk factor for BN, but not for AN, and β3 adrenergic receptor gene nor CCK-AR polymorphism differed between EDs and control subjects.
Development expression of the neural adhesion molecule F3 in the rat brain
TLDR
During postnatal development of the rat brain, cells expressing F3 mRNA appeared in the cortex, hippocampus, superior and inferior colliculi, anterior olfactory nucleus, olfaction bulb and cerebellum, whereas little was observed at postnatal day 1 (P1).
Age-related decline of F3/Contactin in rat hippocampus
TLDR
The specific decrease of F3 in the hippocampus at late stage of aging may be related to memory deficient in old age.
Extensive screening system using suspension array technology to detect mitochondrial DNA point mutations.
TLDR
This genetic screening platform is useful to reach a definitive diagnosis for mitochondrial diseases and designed specific oligonucleotide probes to detect both mutant and wild-type mtDNA, even when polymorphisms were present near the target mutation sites.
Differences in ethanol ingestion between cholecystokinin-A receptor deficient and -B receptor deficient mice.
TLDR
Voluntary ingestion of ethanol differed between CCK-AR(-/-) andCCK-BR (-/-) mice, which might be attributable in part to the different levels of D2R expression in the nucleus accumbens.
Extensive and rapid screening for major mitochondrial DNA point mutations in patients with hereditary hearing loss
TLDR
This study analyzed 373 patients with suspected hereditary HL using an extensive and rapid suspension-array screening system for 29 major mtDNA mutations, including the m.1555A>G homoplasmic mutation in the MT-RNR1 gene, which causes non-syndromic sensorineural HL and aminoglycoside-induced HL.
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