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Transient defects in phagocytic functions during cardiopulmonary bypass.
Phagocytes from 12 patients undergoing cardiopulmonary bypass (CPB) were studied sequentially with the quantitative nitroblue tetrazolium (NBT) test. Leukocytes were obtained 1 day before theExpand
Intergenic complementation after fusion of fibroblasts from different patients with beta-galactosidase deficiency.
Abstract Acid β-galactosidase from human liver consists, after gel filtration at pH 7.0, of a monomeric isoenzyme, β-galactosidase A and small amounts of a multimer, β-galactosidase B (Norden,Expand
Regional localization of aβ-galactosidase locus on human chromosome 22
Human white blood cells with an X/22 translocation [46, XX, t(X; 22)(q23; q13)] were fused with Chinese hamster cells. The isolated hybrids were analyzed for human chromosomes and 21 enzyme markers.Expand
Characterization of beta-D-N-acetylhexosaminidase isoenzymes in man-Chinese hamster somatic cell hybrids.
A series of man-Chinese hamster hybrids were investigated with the use of an anti-Chinese hamster hexosaminidase serum, a specific anti-human hex A serum and an anti-human hex B serum. The expressionExpand
Assignment of structural β-galactosidase loci to human chromosomes 3 and 22
SummaryHybrid cell lines isolated after fusions between Chinese hamster E36 cells and normal human white blood cells were analyzed for human β-galactosidase isoenzymes and for human chromosomes,Expand
The genetic defect in the various types of human β-galactosidase deficiency
SummaryGene localization studies revealed the presence of two structural β-galactosidase (βGAL) loci on the human chromosomes 3 and 22 (de Wit et al., 1979). To determine the function of these genes,Expand
Characterization of residual hexosaminidase activity in Sandhoff's disease using man-Chinese hamster cell hybrids
SummaryTo obtain information about the nature of the residual hexosaminidase activity in Sandhoff's disease, hybrid cell lines between fibroblasts from a patients with Sandhoff's disease and ChineseExpand
Assignment of structural beta-galactosidase loci to human chromosomes 3 and 22.
Hybrid cell lines isolated after fusions between Chinese hamster E36 cells and normal human white blood cells were analyzed for human beta-galactosidase isoenzymes and for human chromosomes,Expand
Regional localization of a beta-galactosidase locus on human chromosome 22.
Human white blood cells with an X/22 translocation [46, XX, t(X;22)(q23;q13)] were fused with Chinese hamster cells. The isolated hybrids were analyzed for human chromosomes and 21 enzyme markers. AnExpand
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