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Identification of a receptor mediating absorption of dietary cholesterol in the intestine.
TLDR
It is shown that scavenger receptor class B type I is present in the small-intestine brush border membrane where it facilitates the uptake of dietary cholesterol from either bile salt micelles or phospholipid vesicles, and binds to high-density lipoprotein and apolipoprotein A-I, which lends further support to the conclusion that scavengers receptor BI catalyzes intestinal cholesterol uptake.
Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol.
TLDR
From the comparison of the in vivo and in vitro results, it is concluded that both BBM-resident class B scavenger receptors, SR-BI and CD36, can facilitate the absorption of beta-carotene and cholesterol.
The structure, physical and chemical properties of the soy bean protein glycinin.
TLDR
The major storage protein of the soybean, glycinin, has been prepared in a homogeneous form and examined by a variety of techniques and revealed three different kinds of acidic subunits and probably three kinds of basic ones also.
Role of scavenger receptors SR-BI and CD36 in selective sterol uptake in the small intestine.
TLDR
It is shown that the mechanism of lipid transfer from reconstituted HDL to either BBMV or Caco-2 cells as the acceptor is consistent with selective lipid uptake: the lipid donor docks at the membrane-resident scavenger receptors which mediate the transfer of lipids between donor and acceptor.
Structure of sterol carrier protein 2 at 1.8 A resolution reveals a hydrophobic tunnel suitable for lipid binding.
TLDR
Structurally well-characterized nonspecific lipid transfer proteins from plants have hydrophobic tunnel-like cavities, which were identified as the binding site for fatty acids and related apolar ligands, suggesting a common functional role.
Interactions of metal ions with phosphatidylserine bilayer membranes: effect of hydrocarbon chain unsaturation.
TLDR
Monitoring the interactions of monovalent and divalent cations with phosphatidylserines differing in their levels of chain unsaturation shows that ion binding to PS depends not only on the properties of the cation but also on the molecular details of the PS membrane surface.
Asymmetric distribution of phospholipids in the inner membrane of beef heart mitochondria.
TLDR
The transversal distribution of phosphatidylcholine, phosph atidylethanolamine, and cardiolipin in the inner membrane of beef heart mitochondria was investigated and indicated cardiolIPin to be about 3 times more abundant on the matrix side of the membrane.
Rabbit small intestinal brush border membrane preparation and lipid composition.
TLDR
Rabbit intestinal brush border membrane vesicles were prepared either from frozen or fresh tissue and the lipid composition was analysed, finding individual phospholipids are characterised by distinct fatty acid compositions and differ markedly in the ratio of unsaturated-to-saturated fatty acid.
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