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Site Specific Induction of Gene Conversion in SCHIZOSACCHAROMYCES POMBE.
- H. Gutz
- Biology, MedicineGenetics
- 1 November 1971
Analysis of DNA repair pathways of Schizosaccharomyces pombe by means of swi-rad double mutants.
In Schizosaccharomyces pombe 11 different switching genes (swi1 to swi10 and rad22) are known which are involved in mating-type (MT) switching, but whether the survival of these mutants after UV irradiation is influenced by caffeine is tested.
Mating-Type Mutations in SCHIZOSACCHAROMYCES POMBE: Isolation of Mutants and Analysis of Strains with an h or h Phenotype.
The results show that the mating-type gene mat2 not only has a function in copulation and meiosis, but that it also regulates the formation of the map1 gene product (map1 is a mating- type auxiliary gene).
Gene activation by copy transposition in mating-type switching of a homothallic fission yeast
Mating-type switching in homothallic clones of the fission yeast, Schizosaccharomyces pombe, appears to follow the same route as previously found for “mutations” from homothallism to heterothallic ⊕ strains, but the unlinked mutations are recessive to their wild-type alleles.
Some of the swi genes of Schizosaccharomyces pombe also have a function in the repair of radiation damage
- H. Schmidt, Petra Kapitza-Fecke, E. R. Stephen, H. Gutz
- Biology, MedicineCurrent Genetics
- 1 August 1989
A cumulative increase in sensitivity occurs only if the mutants belong to different classes; previously the same correlation was found with regard to cumulative effects in MT switching.
Gene conversion: a hitherto overlooked parameter in population genetics.
The influence of gene conversion on allele frequencies is compared with that of spontaneous mutation and meiotic drive and the effects of conversion in a large random-mating population are derived.
The Mating-Type Switch in Yeasts
This chapter will deal with the intriguing process of MT switching, also termed MT interconversion, which involves cells of opposite MT switching in homothallic strains of the yeasts Saccharomyces cerevisiae and S. pombe.
Switching genes in Schizosaccharomyces pombe: their influence on cell viability and recombination
Besides its influence on MT switching, swi5 also reduces the frequencies of meiotic intragenic recombination and gene conversion in the ade6 locus.
A new type of mutation in Schizosaccharomyces pombe: vegetative iodine reaction.
Colonies of Schizosaccharomyces pombe that contain ascospores (e.g., colonies of homothallic strains) turn black after treatment with iodine vapors. Heterothallic strains of S. pombe normally do not…
Gene conversion: remarks on the quantitative implications of hybrid DNA models.
- H. Gutz
- Medicine, BiologyGenetical research
- 1 February 1971
Some peculiarities are discussed which result if, among the corrected fractions of hybrid sites, the frequency of repair to wild-type is the same in both kinds of mispairing.