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Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
A stereological method for obtaining estimates of the total number of neurons in five major subdivisions of the rat hippocampus is described. The new method, the optical fractionator, combines twoExpand
The efficiency of systematic sampling in stereology and its prediction *
TLDR
The superior efficiency of systematic sampling at all levels in stereological studies is emphasized and various commonly used ways of implementing it are briefly described. Expand
The efficiency of systematic sampling in stereology — reconsidered
In the present paper, we summarize and further develop recent research in the estimation of the variance of stereological estimators based on systematic sampling. In particular, it is emphasized thatExpand
Unbiased stereological estimation of the number of neurons in the human hippocampus
The total numbers of neurons in five subdivisions of human hippocampi were estimated using unbiased Stereological principles and systematic sampling techniques. The method addresses the problemsExpand
Neocortical neuron number in humans: Effect of sex and age
Modern stereological methods provide precise and reliable estimates of the number of neurons in specific regions of the brain. We decided to estimate the total number of neocortical neurons in theExpand
Stereology of arbitrary particles *
  • H. Gundersen
  • Mathematics, Medicine
  • Journal of microscopy
  • 1 July 1986
This paper deals with isolated, countable items, often termed particles, in three‐dimensional space. Its substance is the unbiased stereological estimation of the number, height, surface and volumeExpand
Notes on the estimation of the numerical density of arbitrary profiles: the edge effect
A description is given of a family of test‐frames for obtaining an unbiased estimate of the numerical density of arbitrary profiles on a section. The counting rule pertaining to the test‐frame isExpand
The nucleator
A new, fundamental stereological principle is described which allows unbiased estimates of absolute structural quantities in arbitrarily shaped structures to be made from observations sampled inExpand
Tissue shrinkage and unbiased stereological estimation of particle number and size *
This paper is a review of the stereological problems related to the unbiased estimation of particle number and size when tissue deformation is present. The deformation may occur during theExpand
Age-Induced White Matter Changes in the Human Brain: A Stereological Investigation
In the present pilot study, age-related white matter changes were investigated by the use of design-based stereological methods. In the brains of elderly subjects, the total volume of the whiteExpand
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