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Altered Drug Disposition Following Bariatric Surgery: A Research Challenge
Bariatric surgery constitutes an approach to the management of obesity in which the anatomy of the gastrointestinal tract is altered to reduce access of nutrients to absorptive surfaces, to restrictExpand
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Use of Antipsychotics for the Treatment of Behavioral Symptoms of Dementia
Antipsychotic medications are widely used in the management of behavioral and psychological symptoms of dementia. While nonpharmacological interventions should be the first‐line treatment forExpand
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Liver injury associated with ketoconazole: Review of the published evidence
The azole antifungal agent ketoconazole has been available since 1981 for the treatment of fungal infections. In 2013, the American Food and Drug Administration and the European Medicines AgencyExpand
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Visual Analytics Technology Transition Progress
The authors provide a description of the transition process for visual analytic tools and contrast this with the transition process for more traditional software tools. This paper takes thisExpand
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Meldonium (Mildronate): A Performance‐Enhancing Drug?
Meldonium (Mildronate, Mildronāts, Quaterine, MET-88) (Figure 1) is classified by the World AntiDoping Agency (the regulatory body overseeing drug screening for international sporting events) as aExpand
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Antidepressant-Associated Hyponatremia in the Elderly
D epression affects up to 15% of community-dwelling older adults (age > 65 years) in the United States. Among elderly persons with significant medical illnesses, the prevalence of depression may beExpand
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Gabapentin and Pregabalin for the Treatment of Anxiety Disorders
Gabapentin and pregabalin are structurally related compounds which are classified as gammaaminobutyric acid (GABA) analogues or gabapentinoids (Figure 1). Gabapentin, which received American Food andExpand
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Designer Benzodiazepines: A Review of Published Data and Public Health Significance
“Designer drugs,” also referred to as Novel Psychoactive Substances, represent a public health issue of emerging importance. In general, designer drugs are synthetic analogues or derivatives ofExpand
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Stereo‐Psychopharmacology: The Case of Citalopram and Escitalopram
“Chiral switching” is generally defined as the marketing of a single-enantiomer (enantiopure) derivative of a racemic drug that has already been approved.1–3 For example, the proton pump inhibitorExpand
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Ménétrier’s disease presenting as recurrent unprovoked venous thrombosis: a case report
BackgroundAcquired thrombophilia is a potential sequela of malignancy, chronic inflammation, and conditions characterized by severe protein deficiency (for example, nephrotic syndrome, protein-losingExpand
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